JEŽKOVÁ, L, Martin FALK, I FALKOVÁ, M DAVÍDKOVÁ, A BAČÍKOVÁ, Lenka ŠTEFANČÍKOVÁ, J Michaelidesová A VACHELOVÁ, Emilie LUKÁŠOVÁ, A BOREYKO, E KRASAVIN and Stanislav KOZUBEK. Function of chromatin structure and dynamics in DNA damage, repair and misrepair: γ-rays andprotons in action. Applied Radiation and Isotopes. Elsevier, 2014, vol. 83, p. 128-136. ISSN 0969-8043. Available from: https://dx.doi.org/10.1016/j.apradiso.2013.01.022.
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Basic information
Original name Function of chromatin structure and dynamics in DNA damage, repair and misrepair: γ-rays andprotons in action
Authors JEŽKOVÁ, L, Martin FALK, I FALKOVÁ, M DAVÍDKOVÁ, A BAČÍKOVÁ, Lenka ŠTEFANČÍKOVÁ, J Michaelidesová A VACHELOVÁ, Emilie LUKÁŠOVÁ, A BOREYKO, E KRASAVIN and Stanislav KOZUBEK.
Edition Applied Radiation and Isotopes, Elsevier, 2014, 0969-8043.
Other information
Original language English
Type of outcome Article in a journal
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.231
Doi http://dx.doi.org/10.1016/j.apradiso.2013.01.022
Tags International impact, Reviewed
Changed by Changed by: doc. RNDr. Martin Falk, Ph.D., učo 9835. Changed: 19/12/2019 13:50.
Abstract
According to their physical characteristics, protons and ion beams promise a revolution in cancer radiotherapy. Curing protocols however reflect rather the empirical knowledge than experimental data on DNA repair. This especially holds for the spatio-temporal organization of repair processes in the context of higher-order chromatin structure-the problematics addressed in this work. The consequences for the mechanism of chromosomal translocations are compared for gamma rays and proton beams.
Links
GBP302/12/G157, research and development projectName: Dynamika a organizace chromosomů během buněčného cyklu a při diferenciaci v normě a patologii
Investor: Czech Science Foundation
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