Atmospheric Pressure Plasma Polymerized Oxazoline-Based Thin
Films-Antibacterial Properties and Cytocompatibility
Performance

J 2019

Atmospheric Pressure Plasma Polymerized Oxazoline-Based Thin Films-Antibacterial Properties and Cytocompatibility Performance

SŤAHEL, Pavel, Věra MAZÁNKOVÁ, Klára TOMEČKOVÁ, Petra MATOUŠKOVÁ, Antonín BRABLEC et. al.

Basic information

Original name

Atmospheric Pressure Plasma Polymerized Oxazoline-Based Thin Films-Antibacterial Properties and Cytocompatibility Performance

Authors

SŤAHEL, Pavel (203 Czech Republic, guarantor, belonging to the institution), Věra MAZÁNKOVÁ (203 Czech Republic), Klára TOMEČKOVÁ (203 Czech Republic), Petra MATOUŠKOVÁ (203 Czech Republic), Antonín BRABLEC (203 Czech Republic, belonging to the institution), Lubomír PROKEŠ (203 Czech Republic, belonging to the institution), Jana JURMANOVÁ (203 Czech Republic, belonging to the institution), Vilma BURŠÍKOVÁ (203 Czech Republic, belonging to the institution), Roman PŘIBYL (203 Czech Republic, belonging to the institution), Marián LEHOCKÝ (203 Czech Republic), Petr HUMPOLÍČEK (203 Czech Republic), Kadir OZAITIN (203 Czech Republic) and David TRUNEC (203 Czech Republic, belonging to the institution)

Edition

Polymers, Basel, MDPI AG, 2019, 2073-4360

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10305 Fluids and plasma physics

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.426

RIV identification code

RIV/00216224:14310/19:00107887

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.3390/polym11122069

UT WoS

000507624500162

Keywords in English

antibiofouling; plasma polymer; oxazoline

Abstract

V originále

Polyoxazolines are a new promising class of polymers for biomedical applications. Antibiofouling polyoxazoline coatings can suppress bacterial colonization of medical devices, which can cause infections to patients. However, the creation of oxazoline-based films using conventional methods is difficult. This study presents a new way to produce plasma polymerized oxazoline-based films with antibiofouling properties and good biocompatibility. The films were created via plasma deposition from 2-methyl-2-oxazoline vapors in nitrogen atmospheric pressure dielectric barrier discharge. Diverse film properties were achieved by increasing the substrate temperature at the deposition. The physical and chemical properties of plasma polymerized polyoxazoline films were studied by SEM, EDX, FTIR, AFM, depth-sensing indentation technique, and surface energy measurement. After tuning of the deposition parameters, films with a capacity to resist bacterial biofilm formation were achieved. Deposited films also promote cell viability.

Links

GA19-15240S, research and development project

Name: Multifunkční nanokompozitní polymerní tenké vrstvy s řízenými povrchovými a mechanickými vlastnostmi připravené v RF prachovém plazmatu

Investor: Czech Science Foundation

LD15058, research and development project

Name: Příprava substrátů pro povrchově zesílenou Ramanovu spektroskopii pomocí elektrochemických, elektroforetických a jiskrový výboj využívajících technik. (Acronym: ELE-SERS)

Investor: Ministry of Education, Youth and Sports of the CR

LO1411, research and development project

Name: Rozvoj centra pro nízkonákladové plazmové a nanotechnologické povrchové úpravy (Acronym: CEPLANT plus)

Investor: Ministry of Education, Youth and Sports of the CR

Citovat

SŤAHEL, Pavel, Věra MAZÁNKOVÁ, Klára TOMEČKOVÁ, Petra MATOUŠKOVÁ, Antonín BRABLEC, Lubomír PROKEŠ, Jana JURMANOVÁ, Vilma BURŠÍKOVÁ, Roman PŘIBYL, Marián LEHOCKÝ, Petr HUMPOLÍČEK, Kadir OZAITIN and David TRUNEC. Atmospheric Pressure Plasma Polymerized Oxazoline-Based Thin Films-Antibacterial Properties and Cytocompatibility Performance. Polymers. Basel: MDPI AG, 2019, vol. 11, No 12, p. 1-14. ISSN 2073-4360. Available from: https://dx.doi.org/10.3390/polym11122069.

@article{1595997,
   author = {Sťahel, Pavel and Mazánková, Věra and Tomečková, Klára and Matoušková, Petra and Brablec, Antonín and Prokeš, Lubomír and Jurmanová, Jana and Buršíková, Vilma and Přibyl, Roman and Lehocký, Marián and Humpolíček, Petr and Ozaitin, Kadir and Trunec, David},
   article_location = {Basel},
   article_number = {12},
   doi = {http://dx.doi.org/10.3390/polym11122069},
   keywords = {antibiofouling; plasma polymer; oxazoline},
   language = {eng},
   issn = {2073-4360},
   journal = {Polymers},
   title = {Atmospheric Pressure Plasma Polymerized Oxazoline-Based Thin Films-Antibacterial Properties and Cytocompatibility Performance},
   url = {https://www.mdpi.com/2073-4360/11/12/2069},
   volume = {11},
   year = {2019}
}

TY  - JOUR
ID  - 1595997
AU  - Sťahel, Pavel - Mazánková, Věra - Tomečková, Klára - Matoušková, Petra - Brablec, Antonín - Prokeš, Lubomír - Jurmanová, Jana - Buršíková, Vilma - Přibyl, Roman - Lehocký, Marián - Humpolíček, Petr - Ozaitin, Kadir - Trunec, David
PY  - 2019
TI  - Atmospheric Pressure Plasma Polymerized Oxazoline-Based Thin Films-Antibacterial Properties and Cytocompatibility Performance
JF  - Polymers
VL  - 11
IS  - 12
SP  - 1-14
EP  - 1-14
PB  - MDPI AG
SN  - 20734360
KW  - antibiofouling
KW  - plasma polymer
KW  - oxazoline
UR  - https://www.mdpi.com/2073-4360/11/12/2069
L2  - https://www.mdpi.com/2073-4360/11/12/2069
N2  - Polyoxazolines are a new promising class of polymers for biomedical applications. Antibiofouling polyoxazoline coatings can suppress bacterial colonization of medical devices, which can cause infections to patients. However, the creation of oxazoline-based films using conventional methods is difficult. This study presents a new way to produce plasma polymerized oxazoline-based films with antibiofouling properties and good biocompatibility. The films were created via plasma deposition from 2-methyl-2-oxazoline vapors in nitrogen atmospheric pressure dielectric barrier discharge. Diverse film properties were achieved by increasing the substrate temperature at the deposition. The physical and chemical properties of plasma polymerized polyoxazoline films were studied by SEM, EDX, FTIR, AFM, depth-sensing indentation technique, and surface energy measurement. After tuning of the deposition parameters, films with a capacity to resist bacterial biofilm formation were achieved. Deposited films also promote cell viability.
ER  -

SŤAHEL, Pavel, Věra MAZÁNKOVÁ, Klára TOMEČKOVÁ, Petra MATOUŠKOVÁ, Antonín BRABLEC, Lubomír PROKEŠ, Jana JURMANOVÁ, Vilma BURŠÍKOVÁ, Roman PŘIBYL, Marián LEHOCKÝ, Petr HUMPOLÍČEK, Kadir OZAITIN and David TRUNEC. Atmospheric Pressure Plasma Polymerized Oxazoline-Based Thin Films-Antibacterial Properties and Cytocompatibility Performance. \textit{Polymers}. Basel: MDPI AG, 2019, vol.~11, No~12, p.~1-14. ISSN~2073-4360. Available from: https://dx.doi.org/10.3390/polym11122069.

Detailed Information on Publication Record