| FALTINEK, Lukáš, Eva FUJDIAROVÁ, Filip MELICHER, Josef HOUSER, Martina KAŠÁKOVÁ, Nikolay KONDAKOV, Leonid KONONOV, Kamil PARKAN, Sébastien VIDAL and Michaela WIMMEROVÁ. Lectin PLL3, a Novel Monomeric Member of the Seven-Bladed beta-Propeller Lectin Family. Molecules. Basel: MDPI, 2019, vol. 24, No 24, p. 1-20. ISSN 1420-3049. Available from: https://dx.doi.org/10.3390/molecules24244540. |
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@article{1600482,
author = {Faltinek, Lukáš and Fujdiarová, Eva and Melicher, Filip and Houser, Josef and Kašáková, Martina and Kondakov, Nikolay and Kononov, Leonid and Parkan, Kamil and Vidal, Sébastien and Wimmerová, Michaela},
article_location = {Basel},
article_number = {24},
doi = {http://dx.doi.org/10.3390/molecules24244540},
keywords = {Photorhabdus; lectin; O-methylated saccharides; L-fucose},
language = {eng},
issn = {1420-3049},
journal = {Molecules},
title = {Lectin PLL3, a Novel Monomeric Member of the Seven-Bladed beta-Propeller Lectin Family},
url = {https://www.mdpi.com/1420-3049/24/24/4540},
volume = {24},
year = {2019}
}
TY - JOUR
ID - 1600482
AU - Faltinek, Lukáš - Fujdiarová, Eva - Melicher, Filip - Houser, Josef - Kašáková, Martina - Kondakov, Nikolay - Kononov, Leonid - Parkan, Kamil - Vidal, Sébastien - Wimmerová, Michaela
PY - 2019
TI - Lectin PLL3, a Novel Monomeric Member of the Seven-Bladed beta-Propeller Lectin Family
JF - Molecules
VL - 24
IS - 24
SP - 1-20
EP - 1-20
PB - MDPI
SN - 14203049
KW - Photorhabdus
KW - lectin
KW - O-methylated saccharides
KW - L-fucose
UR - https://www.mdpi.com/1420-3049/24/24/4540
L2 - https://www.mdpi.com/1420-3049/24/24/4540
N2 - The Photorhabdus species is a Gram-negative bacteria of the family Morganellaceae that is known for its mutualistic relationship with Heterorhabditis nematodes and pathogenicity toward insects. This study is focused on the characterization of the recombinant lectin PLL3 with an origin in P. laumondii subsp. laumondii. PLL3 belongs to the PLL family of lectins with a seven-bladed beta-propeller fold. The binding properties of PLL3 were tested by hemagglutination assay, glycan array, isothermal titration calorimetry, and surface plasmon resonance, and its structure was determined by X-ray crystallography. Obtained data revealed that PLL3 binds similar carbohydrates to those that the other PLL family members bind, with some differences in the binding properties. PLL3 exhibited the highest affinity toward L-fucose and its derivatives but was also able to interact with O-methylated glycans and other ligands.
ER -
FALTINEK, Lukáš, Eva FUJDIAROVÁ, Filip MELICHER, Josef HOUSER, Martina KAŠÁKOVÁ, Nikolay KONDAKOV, Leonid KONONOV, Kamil PARKAN, Sébastien VIDAL and Michaela WIMMEROVÁ. Lectin PLL3, a Novel Monomeric Member of the Seven-Bladed beta-Propeller Lectin Family. \textit{Molecules}. Basel: MDPI, 2019, vol.~24, No~24, p.~1-20. ISSN~1420-3049. Available from: https://dx.doi.org/10.3390/molecules24244540.
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