| ZABEL, Markus, Simon SCHLOGL, Andrzej LUBINSKI, Jesper Hastrup SVENDSEN, Axel BAUER, Elena ARBELO, Sandro BRUSICH, David CONEN, Iwona CYGANKIEWICZ, Michael DOMMASCH, Panagiota FLEVARI, Jan GALUSZKA, Jim HANSEN, Gerd HASENFUSS, Robert HATALA, Heikki V. HUIKURI, Tuomas KENTTA, Tomasz KUCEJKO, Helge HAARMANN, Markus HARDEN, Svetoslav IOVEV, Stefan KAAB, Gabriela KALISKA, Andreas KATSIMARDOS, Jaroslaw D. KASPRZAK, Dariusz QAVOQ, Lars LUTHJE, Marek MALIK, Tomáš NOVOTNÝ, Nikola PAVLOVIC, Peter PERGE, Christian ROVER, Georg SCHMIDT, Tchavdar SHALGANOV, Rajeeva SRITHARAN, Martin SVETLOSAK, Zoltan SALLO, Janko SZAVITS-NOSSAN, Vassil TRAYKOV, Bert VANDENBERK, Vasil VELCHEV, Marc A. VOS, Stefan N. WILLICH, Tim FRIEDE, Rik WILLEMS, Bela MERKELY and Christian STICHERLING. Present criteria for prophylactic ICD implantation: Insights from the EU-CERT-ICD (Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in EUrope) project. Journal of Electrocardiology. Philadelphia: Churchill Livingstone, 2019, vol. 57, NOV-DEC 201, p. "S34"-"S39", 6 pp. ISSN 0022-0736. Available from: https://dx.doi.org/10.1016/j.jelectrocard.2019.09.001. |
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@article{1604550,
author = {Zabel, Markus and Schlogl, Simon and Lubinski, Andrzej and Svendsen, Jesper Hastrup and Bauer, Axel and Arbelo, Elena and Brusich, Sandro and Conen, David and Cygankiewicz, Iwona and Dommasch, Michael and Flevari, Panagiota and Galuszka, Jan and Hansen, Jim and Hasenfuss, Gerd and Hatala, Robert and Huikuri, Heikki V. and Kentta, Tuomas and Kucejko, Tomasz and Haarmann, Helge and Harden, Markus and Iovev, Svetoslav and Kaab, Stefan and Kaliska, Gabriela and Katsimardos, Andreas and Kasprzak, Jaroslaw D. and Qavoq, Dariusz and Luthje, Lars and Malik, Marek and Novotný, Tomáš and Pavlovic, Nikola and Perge, Peter and Rover, Christian and Schmidt, Georg and Shalganov, Tchavdar and Sritharan, Rajeeva and Svetlosak, Martin and Sallo, Zoltan and SzavitsandNossan, Janko and Traykov, Vassil and Vandenberk, Bert and Velchev, Vasil and Vos, Marc A. and Willich, Stefan N. and Friede, Tim and Willems, Rik and Merkely, Bela and Sticherling, Christian},
article_location = {Philadelphia},
article_number = {NOV-DEC 201},
doi = {http://dx.doi.org/10.1016/j.jelectrocard.2019.09.001},
keywords = {Implantable cardioverter defibrillator; Risk factors; Mortality; Sudden cardiac death},
language = {eng},
issn = {0022-0736},
journal = {Journal of Electrocardiology},
title = {Present criteria for prophylactic ICD implantation: Insights from the EU-CERT-ICD (Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in EUrope) project},
url = {http://dx.doi.org/10.1016/j.jelectrocard.2019.09.001},
volume = {57},
year = {2019}
}
TY - JOUR
ID - 1604550
AU - Zabel, Markus - Schlogl, Simon - Lubinski, Andrzej - Svendsen, Jesper Hastrup - Bauer, Axel - Arbelo, Elena - Brusich, Sandro - Conen, David - Cygankiewicz, Iwona - Dommasch, Michael - Flevari, Panagiota - Galuszka, Jan - Hansen, Jim - Hasenfuss, Gerd - Hatala, Robert - Huikuri, Heikki V. - Kentta, Tuomas - Kucejko, Tomasz - Haarmann, Helge - Harden, Markus - Iovev, Svetoslav - Kaab, Stefan - Kaliska, Gabriela - Katsimardos, Andreas - Kasprzak, Jaroslaw D. - Qavoq, Dariusz - Luthje, Lars - Malik, Marek - Novotný, Tomáš - Pavlovic, Nikola - Perge, Peter - Rover, Christian - Schmidt, Georg - Shalganov, Tchavdar - Sritharan, Rajeeva - Svetlosak, Martin - Sallo, Zoltan - Szavits-Nossan, Janko - Traykov, Vassil - Vandenberk, Bert - Velchev, Vasil - Vos, Marc A. - Willich, Stefan N. - Friede, Tim - Willems, Rik - Merkely, Bela - Sticherling, Christian
PY - 2019
TI - Present criteria for prophylactic ICD implantation: Insights from the EU-CERT-ICD (Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in EUrope) project
JF - Journal of Electrocardiology
VL - 57
IS - NOV-DEC 201
SP - "S34"-"S39"
EP - "S34"-"S39"
PB - Churchill Livingstone
SN - 00220736
KW - Implantable cardioverter defibrillator
KW - Risk factors
KW - Mortality
KW - Sudden cardiac death
UR - http://dx.doi.org/10.1016/j.jelectrocard.2019.09.001
L2 - http://dx.doi.org/10.1016/j.jelectrocard.2019.09.001
N2 - Background: The clinical effectiveness of primary prevention implantable cardioverter defibrillator (ICD) therapy is under debate. It is urgently needed to better identify patients who benefit from prophylactic ICD therapy. The EUropean Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators (EU-CERT-ICD) completed in 2019 will assess this issue. Summary: The EU-CERT-ICD is a prospective investigator-initiated non-randomized, controlled, multicenter observational cohort study done in 44 centers across 15 European countries. A total of 2327 patients with heart failure due to ischemic heart disease or dilated cardiomyopathy indicated for primary prophylactic ICD implantation were recruited between 2014 and 2018 (>1500 patients at first ICD implantation, >750 patients non-randomized non-ICD control group). The primary endpoint was all-cause mortality, and first appropriate shock was co-primary endpoint. At baseline, all patients underwent 12-lead ECG and Holter-ECG analysis using multiple advanced methods for risk stratification as well as documentation of clinical characteristics and laboratory values. The EU-CERT-ICD data will provide much needed information on the survival benefit of preventive ICD therapy and expand on previous prospective risk stratification studies which showed very good applicability of clinical parameters and advanced risk stratifiers in order to define patient subgroups with above or below average ICD benefit. Conclusion: The EU-CERT-ICD study will provide new and current data about effectiveness of primary prophylactic ICD implantation. The study also aims for improved risk stratification and patient selection using clinical risk markers in general, and advanced ECG risk markers in particular. (C) 2019 Elsevier Inc. All rights reserved.
ER -
ZABEL, Markus, Simon SCHLOGL, Andrzej LUBINSKI, Jesper Hastrup SVENDSEN, Axel BAUER, Elena ARBELO, Sandro BRUSICH, David CONEN, Iwona CYGANKIEWICZ, Michael DOMMASCH, Panagiota FLEVARI, Jan GALUSZKA, Jim HANSEN, Gerd HASENFUSS, Robert HATALA, Heikki V. HUIKURI, Tuomas KENTTA, Tomasz KUCEJKO, Helge HAARMANN, Markus HARDEN, Svetoslav IOVEV, Stefan KAAB, Gabriela KALISKA, Andreas KATSIMARDOS, Jaroslaw D. KASPRZAK, Dariusz QAVOQ, Lars LUTHJE, Marek MALIK, Tomáš NOVOTNÝ, Nikola PAVLOVIC, Peter PERGE, Christian ROVER, Georg SCHMIDT, Tchavdar SHALGANOV, Rajeeva SRITHARAN, Martin SVETLOSAK, Zoltan SALLO, Janko SZAVITS-NOSSAN, Vassil TRAYKOV, Bert VANDENBERK, Vasil VELCHEV, Marc A. VOS, Stefan N. WILLICH, Tim FRIEDE, Rik WILLEMS, Bela MERKELY and Christian STICHERLING. Present criteria for prophylactic ICD implantation: Insights from the EU-CERT-ICD (Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in EUrope) project. \textit{Journal of Electrocardiology}. Philadelphia: Churchill Livingstone, 2019, vol.~57, NOV-DEC 201, p.~''S34''-''S39'', 6 pp. ISSN~0022-0736. Available from: https://dx.doi.org/10.1016/j.jelectrocard.2019.09.001.
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