Monophasic synovial sarcoma of the lower extremity at 20 weeks
of pregnancy: a case report and review of the literature

J 2019

Monophasic synovial sarcoma of the lower extremity at 20 weeks of pregnancy: a case report and review of the literature

BIELIKOVA, P., R. PILKA, K. HUML, B. MELICHAR, H. SVEBISOVA et. al.

Základní údaje

Originální název

Monophasic synovial sarcoma of the lower extremity at 20 weeks of pregnancy: a case report and review of the literature

Autoři

BIELIKOVA, P. (203 Česká republika), R. PILKA (203 Česká republika, garant), K. HUML (203 Česká republika), B. MELICHAR (203 Česká republika), H. SVEBISOVA (203 Česká republika), J. JANKOVA (203 Česká republika), V. PRASIL (203 Česká republika), I. ZAMBO (203 Česká republika) a Pavel JANÍČEK (203 Česká republika, domácí)

Vydání

CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY, MONTREAL, 7847050 CANADA INC, 2019, 0390-6663

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30214 Obstetrics and gynaecology

Stát vydavatele

Kanada

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 0.139

Kód RIV

RIV/00216224:14110/19:00112434

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.12891/ceog4877.2019

UT WoS

000503058000031

Klíčová slova anglicky

Synovial sarcoma; Malignancy; Pregnancy; Limb-sparing surgery

Štítky

14110123, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 16. 1. 2020 08:12, Mgr. Tereza Miškechová

Anotace

V originále

Introduction: The incidence of malignancy in pregnancy is reported to range approximately between 0.02% and 1%. Synovial sarcoma (SS) is a rare aggressive mesenchymal tumor for which there are no treatment guidelines during pregnancy. Case Report: The authors report a 23-year-old primigravida presenting. at 20+0 weeks of pregnancy. with a growing painful mass in the left thigh. The diagnosis of monophasic SS grade 3 was confirmed by the presence of SYT gene fusion. On MRI scan there was a heterogeneous localized mass of size 75 x115 x103 mm, but there was no evidence of distant metastases. Limb-sparing surgery with clear-surgical margins was performed at 26+3 weeks of pregnancy. Adjuvant chemotherapy with two cycles of doxorubicin was followed by delivery of normal child by caesarean section at 36+3 weeks of pregnancy. Adjuvant radiotherapy of total dose of 66 Gray to the site of the resection had been administered followed by two cycles of doxorubicin. Conclusion: The patient is free of recurrence six months after the completion of the treatment.

Citovat

BIELIKOVA, P., R. PILKA, K. HUML, B. MELICHAR, H. SVEBISOVA, J. JANKOVA, V. PRASIL, I. ZAMBO a Pavel JANÍČEK. Monophasic synovial sarcoma of the lower extremity at 20 weeks of pregnancy: a case report and review of the literature. CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY. MONTREAL: 7847050 CANADA INC, 2019, roč. 46, č. 6, s. 992-998. ISSN 0390-6663. Dostupné z: https://dx.doi.org/10.12891/ceog4877.2019.

@article{1604801,
   author = {Bielikova, P. and Pilka, R. and Huml, K. and Melichar, B. and Svebisova, H. and Jankova, J. and Prasil, V. and Zambo, I. and Janíček, Pavel},
   article_location = {MONTREAL},
   article_number = {6},
   doi = {http://dx.doi.org/10.12891/ceog4877.2019},
   keywords = {Synovial sarcoma; Malignancy; Pregnancy; Limb-sparing surgery},
   language = {eng},
   issn = {0390-6663},
   journal = {CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY},
   title = {Monophasic synovial sarcoma of the lower extremity at 20 weeks of pregnancy: a case report and review of the literature},
   url = {http://dx.doi.org/10.12891/ceog4877.2019},
   volume = {46},
   year = {2019}
}

TY  - JOUR
ID  - 1604801
AU  - Bielikova, P. - Pilka, R. - Huml, K. - Melichar, B. - Svebisova, H. - Jankova, J. - Prasil, V. - Zambo, I. - Janíček, Pavel
PY  - 2019
TI  - Monophasic synovial sarcoma of the lower extremity at 20 weeks of pregnancy: a case report and review of the literature
JF  - CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY
VL  - 46
IS  - 6
SP  - 992-998
EP  - 992-998
PB  - 7847050 CANADA INC
SN  - 03906663
KW  - Synovial sarcoma
KW  - Malignancy
KW  - Pregnancy
KW  - Limb-sparing surgery
UR  - http://dx.doi.org/10.12891/ceog4877.2019
L2  - http://dx.doi.org/10.12891/ceog4877.2019
N2  - Introduction: The incidence of malignancy in pregnancy is reported to range approximately between 0.02% and 1%. Synovial sarcoma (SS) is a rare aggressive mesenchymal tumor for which there are no treatment guidelines during pregnancy. Case Report: The authors report a 23-year-old primigravida presenting. at 20+0 weeks of pregnancy. with a growing painful mass in the left thigh. The diagnosis of monophasic SS grade 3 was confirmed by the presence of SYT gene fusion. On MRI scan there was a heterogeneous localized mass of size 75 x115 x103 mm, but there was no evidence of distant metastases. Limb-sparing surgery with clear-surgical margins was performed at 26+3 weeks of pregnancy. Adjuvant chemotherapy with two cycles of doxorubicin was followed by delivery of normal child by caesarean section at 36+3 weeks of pregnancy. Adjuvant radiotherapy of total dose of 66 Gray to the site of the resection had been administered followed by two cycles of doxorubicin. Conclusion: The patient is free of recurrence six months after the completion of the treatment.
ER  -

BIELIKOVA, P., R. PILKA, K. HUML, B. MELICHAR, H. SVEBISOVA, J. JANKOVA, V. PRASIL, I. ZAMBO a Pavel JANÍČEK. Monophasic synovial sarcoma of the lower extremity at 20 weeks of pregnancy: a case report and review of the literature. \textit{CLINICAL AND EXPERIMENTAL OBSTETRICS \&{}amp; GYNECOLOGY}. MONTREAL: 7847050 CANADA INC, 2019, roč.~46, č.~6, s.~992-998. ISSN~0390-6663. Dostupné z: https://dx.doi.org/10.12891/ceog4877.2019.

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