| BIELIKOVA, P., R. PILKA, K. HUML, B. MELICHAR, H. SVEBISOVA, J. JANKOVA, V. PRASIL, I. ZAMBO and Pavel JANÍČEK. Monophasic synovial sarcoma of the lower extremity at 20 weeks of pregnancy: a case report and review of the literature. CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY. MONTREAL: 7847050 CANADA INC, 2019, vol. 46, No 6, p. 992-998. ISSN 0390-6663. Available from: https://dx.doi.org/10.12891/ceog4877.2019. |
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@article{1604801,
author = {Bielikova, P. and Pilka, R. and Huml, K. and Melichar, B. and Svebisova, H. and Jankova, J. and Prasil, V. and Zambo, I. and Janíček, Pavel},
article_location = {MONTREAL},
article_number = {6},
doi = {http://dx.doi.org/10.12891/ceog4877.2019},
keywords = {Synovial sarcoma; Malignancy; Pregnancy; Limb-sparing surgery},
language = {eng},
issn = {0390-6663},
journal = {CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY},
title = {Monophasic synovial sarcoma of the lower extremity at 20 weeks of pregnancy: a case report and review of the literature},
url = {http://dx.doi.org/10.12891/ceog4877.2019},
volume = {46},
year = {2019}
}
TY - JOUR
ID - 1604801
AU - Bielikova, P. - Pilka, R. - Huml, K. - Melichar, B. - Svebisova, H. - Jankova, J. - Prasil, V. - Zambo, I. - Janíček, Pavel
PY - 2019
TI - Monophasic synovial sarcoma of the lower extremity at 20 weeks of pregnancy: a case report and review of the literature
JF - CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY
VL - 46
IS - 6
SP - 992-998
EP - 992-998
PB - 7847050 CANADA INC
SN - 03906663
KW - Synovial sarcoma
KW - Malignancy
KW - Pregnancy
KW - Limb-sparing surgery
UR - http://dx.doi.org/10.12891/ceog4877.2019
L2 - http://dx.doi.org/10.12891/ceog4877.2019
N2 - Introduction: The incidence of malignancy in pregnancy is reported to range approximately between 0.02% and 1%. Synovial sarcoma (SS) is a rare aggressive mesenchymal tumor for which there are no treatment guidelines during pregnancy. Case Report: The authors report a 23-year-old primigravida presenting. at 20+0 weeks of pregnancy. with a growing painful mass in the left thigh. The diagnosis of monophasic SS grade 3 was confirmed by the presence of SYT gene fusion. On MRI scan there was a heterogeneous localized mass of size 75 x115 x103 mm, but there was no evidence of distant metastases. Limb-sparing surgery with clear-surgical margins was performed at 26+3 weeks of pregnancy. Adjuvant chemotherapy with two cycles of doxorubicin was followed by delivery of normal child by caesarean section at 36+3 weeks of pregnancy. Adjuvant radiotherapy of total dose of 66 Gray to the site of the resection had been administered followed by two cycles of doxorubicin. Conclusion: The patient is free of recurrence six months after the completion of the treatment.
ER -
BIELIKOVA, P., R. PILKA, K. HUML, B. MELICHAR, H. SVEBISOVA, J. JANKOVA, V. PRASIL, I. ZAMBO and Pavel JANÍČEK. Monophasic synovial sarcoma of the lower extremity at 20 weeks of pregnancy: a case report and review of the literature. \textit{CLINICAL AND EXPERIMENTAL OBSTETRICS \&{}amp; GYNECOLOGY}. MONTREAL: 7847050 CANADA INC, 2019, vol.~46, No~6, p.~992-998. ISSN~0390-6663. Available from: https://dx.doi.org/10.12891/ceog4877.2019.
|
