Selective coronary angiography, percutaneous coronary intervention and asymptomatic peri-procedural myocardial injury

GRIVA, Martin, Jiri STASTNY, Petr KOPRIVA, Martin SLABAK, Zdenek COUFAL, Jiří JARKOVSKÝ, Michal SVOBODA, Tomas SALEK, Lucie SUKUPOVA and Milos TABORSKY. Selective coronary angiography, percutaneous coronary intervention and asymptomatic peri-procedural myocardial injury. Biomedical Papers. Olomouc: Palacky University, 2019, vol. 163, No 4, p. 324-330. ISSN 1213-8118. Available from: https://dx.doi.org/10.5507/bp.2018.066.

Basic information

Original name

Selective coronary angiography, percutaneous coronary intervention and asymptomatic peri-procedural myocardial injury

Authors

GRIVA, Martin (203 Czech Republic, guarantor), Jiri STASTNY (203 Czech Republic), Petr KOPRIVA (203 Czech Republic), Martin SLABAK (203 Czech Republic), Zdenek COUFAL (203 Czech Republic), Jiří JARKOVSKÝ (203 Czech Republic, belonging to the institution), Michal SVOBODA (203 Czech Republic, belonging to the institution), Tomas SALEK (203 Czech Republic), Lucie SUKUPOVA (203 Czech Republic) and Milos TABORSKY (203 Czech Republic)

Edition

Biomedical Papers, Olomouc, Palacky University, 2019, 1213-8118

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Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 1.000

RIV identification code

RIV/00216224:14110/19:00112748

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.5507/bp.2018.066

UT WoS

000506054400006

Keywords in English

coronary angiography; percutaneous coronary intervention; high-sensitivity troponin; periprocedural myocardial injury

Tags

14119612, rivok

Tags

International impact, Reviewed

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Abstract

V originále

Background. While there have been a number of studies reporting the incidence and implications of elevated troponin levels after percutaneous coronary intervention (PCI), the body of information about the incidence, associations, and implications of elevated troponin levels following coronary angiography (CAG) is limited. Materials and Methods. A total of 220 consecutive patients with stable coronary artery disease or intermediate or low-risk acute coronary syndrome without persistent ST-segment elevation (NSTE-ACS) were included in our study. High-sensitivity cardiac troponin I (hs-cTnI) levels were measured before and after coronary angiography (CAG) in patients with or without PCI and correlated with a number of clinical variables. Results. Hs-cTnl elevations above the 99th percentile upper reference limit (URL), or above 20% of the initially positive, yet already declining values, were found in 60 (37.2%) patients after CAG and in 45 (76.2%) patients undergoing PCI. Significant correlations of hs-cTnI elevation were found with the following variables: volume of contrast, fluoroscopy time, dose-area product, amount of contrast agent injected directly into the coronary arteries, total time of balloon dilation and the number and total length of implanted stents (P<0.001 for all). Conclusion. While an asymptomatic elevation of hs-cTnl is a common finding after PCI, it does occur, quite surprisingly, also after CAG. Despite contradictory views regarding the clinical relevance of asymptomatic post-procedural elevated hs-cTnl levels, it is generally believed that a mild elevation is not associated with an increased risk. Still, it may pose a diagnostic quandary following a successful interventional procedure and even more so after an uncomplicated CAG.