BENTAL, Ido, Peter SOLÁR, Shahaf LEVIN, Alemeh ZAMANI, Petr DUBOVÝ and Marek JOUKAL. Expression of toll-like and formyl peptide receptors in choroid plexus after subarachnoid hemorrhage. In Morphology 2019. 2019. ISBN 978-80-8152-758-6.
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Basic information
Original name Expression of toll-like and formyl peptide receptors in choroid plexus after subarachnoid hemorrhage
Authors BENTAL, Ido (376 Israel, belonging to the institution), Peter SOLÁR (703 Slovakia, belonging to the institution), Shahaf LEVIN (376 Israel, belonging to the institution), Alemeh ZAMANI (364 Islamic Republic of Iran, belonging to the institution), Petr DUBOVÝ (203 Czech Republic, belonging to the institution) and Marek JOUKAL (203 Czech Republic, guarantor, belonging to the institution).
Edition Morphology 2019, 2019.
Other information
Original language English
Type of outcome Conference abstract
Field of Study 30106 Anatomy and morphology
Country of publisher Slovakia
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/19:00112776
Organization unit Faculty of Medicine
ISBN 978-80-8152-758-6
Keywords in English choroid plexus; subarachnoid hemorrhage; toll-like and formyl peptide receptors
Tags rivok
Tags International impact
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 29/1/2020 11:15.
Abstract
A subarachnoid hemorrhage is a life threatening state, which can be caused by aneurysm rupture, arteriovenous malformation or trauma. In our previous experiments, we found cellular immune reaction in choroid plexus after SAH. Therefore, the main aim of presented study was to investigate receptor mediated reaction to SAH. We focused on the expression of toll-like receptors (TLR) 4, 9 and formyl-peptide receptor (FPR) 2 after SAH. Material and Methods: The experiments were performed on 16 Wistar rats (males, 250g). SAH was induced by injection of blood into the cisterna magna, while control group received artificial CSF. The animals were left to survive for 1, 3 and 7 days from the application. After time of survival, the SAH and control together with naive rats were perfused transcardially with Zamboni´s fixative. Coronal cryostat sections through the brains were cut and immunostained for TLR4, TLR9 and FPR2.
Links
MUNI/A/1086/2018, interní kód MUName: Reakce struktur nervové soustavy na poškození
Investor: Masaryk University, Category A
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