Nitric oxide affects cadmium-induced changes in the lichen
Ramalina farinacea

J 2019

Nitric oxide affects cadmium-induced changes in the lichen Ramalina farinacea

KOVACIK, Jozef, Slawomir DRESLER, Giuseppe MICALIZZI, Petr BABULA, Juraj HLADKY et. al.

Basic information

Original name

Nitric oxide affects cadmium-induced changes in the lichen Ramalina farinacea

Authors

KOVACIK, Jozef (703 Slovakia, guarantor), Slawomir DRESLER (616 Poland), Giuseppe MICALIZZI (380 Italy), Petr BABULA (203 Czech Republic, belonging to the institution), Juraj HLADKY (703 Slovakia) and Luigi MONDELLO (380 Italy)

Edition

NITRIC OXIDE-BIOLOGY AND CHEMISTRY, SAN DIEGO, ACADEMIC PRESS INC ELSEVIER SCIENCE, 2019, 1089-8603

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10608 Biochemistry and molecular biology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.311

RIV identification code

RIV/00216224:14110/19:00112789

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.niox.2018.12.001

UT WoS

000456636100002

Keywords in English

Antioxidants; Fluorescence microscopy; Heavy metals; Oxidative stress; Photobiont; Polyunsaturated fatty acids

Abstract

V originále

Metabolic responses of epiphytic lichen Ramalina farinacea to cadmium (Cd) and/or nitric oxide (NO) scavenger (cPTIO) were studied. Accumulation of Cd and other metallic nutrients was not affected by cPTIO while total and absorbed amounts differed. Cd-induced NO formation was suppressed by cPTIO but ROS signal was synergistically enhanced, confirming that NO is essential to keep ROS under control. This excessive ROS generation could be a reason for depleted amount of all fatty acids, including SFAs, MUFAs and PUFAs. Total content of fatty acids reached 3.89 mg/g DW in control with linoleic (40%), palmitic (24%), oleic (12.8%) and stearic (8%) acids as major compounds: interestingly, shift in relative ratio of saturated (from 40 to 35% of total FM) versus polyunsaturated fatty acids (from 42 to 48% of total FM) was observed. Glutathione was suppressed by all treatments but Krebs acids were almost unaffected by cPTIO, indicating no regulatory role of NO in their accumulation. On the contrary, Cd-induced elevation in NO signal was related to increase in ascorbate and proline content while cPTIO suppressed it, indicating a tight relation between NO and these metabolites. Data are compared also with algae and vascular plants to show similarities between various life lineages.

Citovat

KOVACIK, Jozef, Slawomir DRESLER, Giuseppe MICALIZZI, Petr BABULA, Juraj HLADKY and Luigi MONDELLO. Nitric oxide affects cadmium-induced changes in the lichen Ramalina farinacea. NITRIC OXIDE-BIOLOGY AND CHEMISTRY. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2019, vol. 83, FEB 1 2019, p. 11-18. ISSN 1089-8603. Available from: https://dx.doi.org/10.1016/j.niox.2018.12.001.

@article{1612167,
   author = {Kovacik, Jozef and Dresler, Slawomir and Micalizzi, Giuseppe and Babula, Petr and Hladky, Juraj and Mondello, Luigi},
   article_location = {SAN DIEGO},
   article_number = {FEB 1 2019},
   doi = {http://dx.doi.org/10.1016/j.niox.2018.12.001},
   keywords = {Antioxidants; Fluorescence microscopy; Heavy metals; Oxidative stress; Photobiont; Polyunsaturated fatty acids},
   language = {eng},
   issn = {1089-8603},
   journal = {NITRIC OXIDE-BIOLOGY AND CHEMISTRY},
   title = {Nitric oxide affects cadmium-induced changes in the lichen Ramalina farinacea},
   url = {http://dx.doi.org/10.1016/j.niox.2018.12.001},
   volume = {83},
   year = {2019}
}

TY  - JOUR
ID  - 1612167
AU  - Kovacik, Jozef - Dresler, Slawomir - Micalizzi, Giuseppe - Babula, Petr - Hladky, Juraj - Mondello, Luigi
PY  - 2019
TI  - Nitric oxide affects cadmium-induced changes in the lichen Ramalina farinacea
JF  - NITRIC OXIDE-BIOLOGY AND CHEMISTRY
VL  - 83
IS  - FEB 1 2019
SP  - 11-18
EP  - 11-18
PB  - ACADEMIC PRESS INC ELSEVIER SCIENCE
SN  - 10898603
KW  - Antioxidants
KW  - Fluorescence microscopy
KW  - Heavy metals
KW  - Oxidative stress
KW  - Photobiont
KW  - Polyunsaturated fatty acids
UR  - http://dx.doi.org/10.1016/j.niox.2018.12.001
L2  - http://dx.doi.org/10.1016/j.niox.2018.12.001
N2  - Metabolic responses of epiphytic lichen Ramalina farinacea to cadmium (Cd) and/or nitric oxide (NO) scavenger (cPTIO) were studied. Accumulation of Cd and other metallic nutrients was not affected by cPTIO while total and absorbed amounts differed. Cd-induced NO formation was suppressed by cPTIO but ROS signal was synergistically enhanced, confirming that NO is essential to keep ROS under control. This excessive ROS generation could be a reason for depleted amount of all fatty acids, including SFAs, MUFAs and PUFAs. Total content of fatty acids reached 3.89 mg/g DW in control with linoleic (40%), palmitic (24%), oleic (12.8%) and stearic (8%) acids as major compounds: interestingly, shift in relative ratio of saturated (from 40 to 35% of total FM) versus polyunsaturated fatty acids (from 42 to 48% of total FM) was observed. Glutathione was suppressed by all treatments but Krebs acids were almost unaffected by cPTIO, indicating no regulatory role of NO in their accumulation. On the contrary, Cd-induced elevation in NO signal was related to increase in ascorbate and proline content while cPTIO suppressed it, indicating a tight relation between NO and these metabolites. Data are compared also with algae and vascular plants to show similarities between various life lineages.
ER  -

KOVACIK, Jozef, Slawomir DRESLER, Giuseppe MICALIZZI, Petr BABULA, Juraj HLADKY and Luigi MONDELLO. Nitric oxide affects cadmium-induced changes in the lichen Ramalina farinacea. \textit{NITRIC OXIDE-BIOLOGY AND CHEMISTRY}. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2019, vol.~83, FEB 1 2019, p.~11-18. ISSN~1089-8603. Available from: https://dx.doi.org/10.1016/j.niox.2018.12.001.

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