Other formats:
BibTeX
LaTeX
RIS
@proceedings{1613325, author = {Peschelová, Helena and Kozlová, Veronika and Hejret, Václav and Šmída, Michal}, booktitle = {Joint retreat 2019, Kouty u Ledče nad Sázavou}, keywords = {CRISPR/Cas9; chronic lymphocytic leukemia}, language = {eng}, isbn = {978-80-210-9300-3}, title = {CRISPR/Cas9 gene editing and functional screening in chronic lymphocytic leukemia}, url = {http://phdretreat.ceitec.cz/download/220}, year = {2019} }
TY - CONF ID - 1613325 AU - Peschelová, Helena - Kozlová, Veronika - Hejret, Václav - Šmída, Michal PY - 2019 TI - CRISPR/Cas9 gene editing and functional screening in chronic lymphocytic leukemia SN - 9788021093003 KW - CRISPR/Cas9 KW - chronic lymphocytic leukemia UR - http://phdretreat.ceitec.cz/download/220 L2 - http://phdretreat.ceitec.cz/download/220 N2 - Chronic lymphocytic leukemia (CLL) patients carry a variety of somatic mutations, whose thorough exploration could shed light on the etiology of the disease, or even lead to the discovery of potential novel drug targets. However, as primary CLL cells do not proliferate in vitro, there is a lack of suitable models mimicking the genetic heterogeneity observed in patients. Our aim is to establish isogenic cell lines harboring the most frequent CLL mutations and to investigate unique vulnerabilities specific to these mutations. ER -
PESCHELOVÁ, Helena, Veronika KOZLOVÁ, Václav HEJRET and Michal ŠMÍDA. CRISPR/Cas9 gene editing and functional screening in chronic lymphocytic leukemia. In \textit{Joint retreat 2019, Kouty u Ledče nad Sázavou}. 2019. ISBN~978-80-210-9300-3.
|