JACKOVÁ, Jana, Petra ŠEDOVÁ, Robert D., Jr. BROWN, Miroslav ZVOLSKÝ, Silvie BĚLAŠKOVÁ, Michaela VOLNÁ, Jana BALUCHOVÁ, Josef BEDNAŘÍK and Robert MIKULÍK. Risk Factors in Ischemic Stroke Subtypes: a Community-Based Study in Brno, Czech Republic. Journal of Stroke & Cerebrovascular Diseases. Amsterdam: Elsevier, 2020, vol. 29, No 2, p. 1-8. ISSN 1052-3057. Available from: https://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2019.104503.
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Basic information
Original name Risk Factors in Ischemic Stroke Subtypes: a Community-Based Study in Brno, Czech Republic
Authors JACKOVÁ, Jana (703 Slovakia, belonging to the institution), Petra ŠEDOVÁ (203 Czech Republic, belonging to the institution), Robert D., Jr. BROWN (840 United States of America), Miroslav ZVOLSKÝ (203 Czech Republic), Silvie BĚLAŠKOVÁ (203 Czech Republic), Michaela VOLNÁ (203 Czech Republic), Jana BALUCHOVÁ (203 Czech Republic), Josef BEDNAŘÍK (203 Czech Republic, belonging to the institution) and Robert MIKULÍK (203 Czech Republic, guarantor, belonging to the institution).
Edition Journal of Stroke & Cerebrovascular Diseases, Amsterdam, Elsevier, 2020, 1052-3057.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30103 Neurosciences
Country of publisher Netherlands
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 2.136
RIV identification code RIV/00216224:14110/20:00115307
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2019.104503
UT WoS 000505793800045
Keywords in English Stroke; ischemic stroke subtypes; TOAST classification; risk factors; Czech Republic
Tags 14110127, 14110212, 14110221, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 8/2/2021 14:07.
Abstract
Background: It is not known if risk factors differ between ischemic stroke (IS) subtypes in Central and Eastern Europe. Aims: We performed a community-based analysis of risk factors in patients admitted with IS over a 1 year period in Brno, the second largest city in the Czech Republic (CR). Methods: Based on the National Register of Hospitalized Patients, all patients with IS admitted in Brno in 2011 were identified. Comprehensive discharge summaries from hospital admissions were collected and reviewed. IS subtype and relevant risk factors were ascertained for all patients. The age- and sex-adjusted association of risk factors with IS subtypes was determined. Results: Overall, 682 patients with IS were admitted in 2011 to Brno hospitals. The distribution of IS subtypes was: 35% cardioembolism, 28% large-artery atherosclerosis, 23% small-artery occlusion, 7% stroke of undetermined etiology, 7% stroke of other determined etiology. Several of the risk factors showed high prevalence in the overall sample - e.g. hypertension (84%) and hyperlipidemia (61%). Cardioembolism as compared to other subtypes was positively associated with a history of myocardial infarction, cardiac failure, and atrial fibrillation. Small-artery occlusion was positively associated with history of dementia. No significant association was found between IS subtypes and history of IS, hypertension, diabetes, obesity, alcohol abuse or smoking. Conclusions: We found high frequency of stroke risk factors in all IS subtypes. These findings have implications for stroke prevention strategies in the CR and across Central Europe.
Links
LM2015090, research and development projectName: Český národní uzel Evropské sítě infrastruktur klinického výzkumu (Acronym: CZECRIN)
Investor: Ministry of Education, Youth and Sports of the CR
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