Detailed Information on Publication Record
2020
Risk Factors in Ischemic Stroke Subtypes: a Community-Based Study in Brno, Czech Republic
JACKOVÁ, Jana, Petra ŠEDOVÁ, Robert D., Jr. BROWN, Miroslav ZVOLSKÝ, Silvie BĚLAŠKOVÁ et. al.Basic information
Original name
Risk Factors in Ischemic Stroke Subtypes: a Community-Based Study in Brno, Czech Republic
Authors
JACKOVÁ, Jana (703 Slovakia, belonging to the institution), Petra ŠEDOVÁ (203 Czech Republic, belonging to the institution), Robert D., Jr. BROWN (840 United States of America), Miroslav ZVOLSKÝ (203 Czech Republic), Silvie BĚLAŠKOVÁ (203 Czech Republic), Michaela VOLNÁ (203 Czech Republic), Jana BALUCHOVÁ (203 Czech Republic), Josef BEDNAŘÍK (203 Czech Republic, belonging to the institution) and Robert MIKULÍK (203 Czech Republic, guarantor, belonging to the institution)
Edition
Journal of Stroke & Cerebrovascular Diseases, Amsterdam, Elsevier, 2020, 1052-3057
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30103 Neurosciences
Country of publisher
Netherlands
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 2.136
RIV identification code
RIV/00216224:14110/20:00115307
Organization unit
Faculty of Medicine
UT WoS
000505793800045
Keywords in English
Stroke; ischemic stroke subtypes; TOAST classification; risk factors; Czech Republic
Tags
International impact, Reviewed
Změněno: 8/2/2021 14:07, Mgr. Tereza Miškechová
Abstract
V originále
Background: It is not known if risk factors differ between ischemic stroke (IS) subtypes in Central and Eastern Europe. Aims: We performed a community-based analysis of risk factors in patients admitted with IS over a 1 year period in Brno, the second largest city in the Czech Republic (CR). Methods: Based on the National Register of Hospitalized Patients, all patients with IS admitted in Brno in 2011 were identified. Comprehensive discharge summaries from hospital admissions were collected and reviewed. IS subtype and relevant risk factors were ascertained for all patients. The age- and sex-adjusted association of risk factors with IS subtypes was determined. Results: Overall, 682 patients with IS were admitted in 2011 to Brno hospitals. The distribution of IS subtypes was: 35% cardioembolism, 28% large-artery atherosclerosis, 23% small-artery occlusion, 7% stroke of undetermined etiology, 7% stroke of other determined etiology. Several of the risk factors showed high prevalence in the overall sample - e.g. hypertension (84%) and hyperlipidemia (61%). Cardioembolism as compared to other subtypes was positively associated with a history of myocardial infarction, cardiac failure, and atrial fibrillation. Small-artery occlusion was positively associated with history of dementia. No significant association was found between IS subtypes and history of IS, hypertension, diabetes, obesity, alcohol abuse or smoking. Conclusions: We found high frequency of stroke risk factors in all IS subtypes. These findings have implications for stroke prevention strategies in the CR and across Central Europe.
Links
| LM2015090, research and development project |
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