Electrochemical determination of insulin at
CuNPs/chitosan-MWCNTs and CoNPs/chitosan-MWCNTs modified screen
printed carbon electrodes

J 2020

Electrochemical determination of insulin at CuNPs/chitosan-MWCNTs and CoNPs/chitosan-MWCNTs modified screen printed carbon electrodes

ŠIŠOLÁKOVÁ, Ivana, Jana HOVANCOVÁ, Renáta ORIŇAKOVÁ, Andrej ORIŇAK, Libuše TRNKOVÁ et. al.

Basic information

Original name

Electrochemical determination of insulin at CuNPs/chitosan-MWCNTs and CoNPs/chitosan-MWCNTs modified screen printed carbon electrodes

Authors

ŠIŠOLÁKOVÁ, Ivana (703 Slovakia), Jana HOVANCOVÁ (703 Slovakia), Renáta ORIŇAKOVÁ (703 Slovakia, guarantor), Andrej ORIŇAK (703 Slovakia), Libuše TRNKOVÁ (203 Czech Republic, belonging to the institution), Iveta TŘÍSKOVÁ (203 Czech Republic, belonging to the institution), Zdeněk FARKA (203 Czech Republic, belonging to the institution), Matěj PASTUCHA (203 Czech Republic, belonging to the institution) and Jozef RADOŇÁK (703 Slovakia)

Edition

Journal of Electroanalytical Chemistry, Lausanne, Elsevier, 2020, 1572-6657

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10406 Analytical chemistry

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 4.464

RIV identification code

RIV/00216224:14310/20:00115315

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.1016/j.jelechem.2020.113881

UT WoS

000519336100002

Keywords in English

Insulin; Screen printed carbon electrodes; Copper nanoparticles; Cobalt nanoparticles; Electrochemical determination

Abstract

V originále

Transition metal nanoparticles can be considered as promising low cost materials for insulin oxidation catalysis. Combination of transition metal nanoparticles with multi walled carbon nanotubes (MWCNTs), which enlarges the active surface area of the electrode, can improve the analytical characteristics of electrodes. Two types of screen printed carbon electrodes (SPCEs) modified by the combination of copper (CuNPs) or cobalt (CoNPs) nanoparticles with chitosan and MWCNTs were prepared. In the effort to find the most suitable modification for electrochemical insulin determination, stability, analytical characteristics and selectivity of both electrode types were compared. The results proved better stability and analytical characteristics with no significant influence of interferences on insulin determination at CoNPs/chitosan-MWCNTs/SPCE. These electrodes provided low limit of detection (25 nM), high sensitivity (0.031 mA uM-1) and wide linear range (0.05 uM to 5 uM) for insulin determination. The stability of the CoNPs/chitosan-MWCNTs/SPCE was very high, with only 1.7% decrease of maximal current value after 50 measurements. Therefore, CoNPs/chitosan-MWCNTs/SPCE can be considered as the suitable modification for new electrochemical sensor for insulin determination, with better analytical characteristics in comparison with SPCE modification using MWCNTs, chitosan and CuNPs described in this study.

Links

LM2018127, research and development project

Name: Česká infrastruktura pro integrativní strukturní biologii (Acronym: CIISB)

Investor: Ministry of Education, Youth and Sports of the CR

Citovat

ŠIŠOLÁKOVÁ, Ivana, Jana HOVANCOVÁ, Renáta ORIŇAKOVÁ, Andrej ORIŇAK, Libuše TRNKOVÁ, Iveta TŘÍSKOVÁ, Zdeněk FARKA, Matěj PASTUCHA and Jozef RADOŇÁK. Electrochemical determination of insulin at CuNPs/chitosan-MWCNTs and CoNPs/chitosan-MWCNTs modified screen printed carbon electrodes. Journal of Electroanalytical Chemistry. Lausanne: Elsevier, 2020, vol. 860, MAR 1 2020, p. 1-9. ISSN 1572-6657. Available from: https://dx.doi.org/10.1016/j.jelechem.2020.113881.

@article{1620561,
   author = {Šišoláková, Ivana and Hovancová, Jana and Oriňaková, Renáta and Oriňak, Andrej and Trnková, Libuše and Třísková, Iveta and Farka, Zdeněk and Pastucha, Matěj and Radoňák, Jozef},
   article_location = {Lausanne},
   article_number = {MAR 1 2020},
   doi = {http://dx.doi.org/10.1016/j.jelechem.2020.113881},
   keywords = {Insulin; Screen printed carbon electrodes; Copper nanoparticles; Cobalt nanoparticles; Electrochemical determination},
   language = {eng},
   issn = {1572-6657},
   journal = {Journal of Electroanalytical Chemistry},
   title = {Electrochemical determination of insulin at CuNPs/chitosan-MWCNTs and CoNPs/chitosan-MWCNTs modified screen printed carbon electrodes},
   url = {https://www.sciencedirect.com/science/article/pii/S1572665720300643},
   volume = {860},
   year = {2020}
}

TY  - JOUR
ID  - 1620561
AU  - Šišoláková, Ivana - Hovancová, Jana - Oriňaková, Renáta - Oriňak, Andrej - Trnková, Libuše - Třísková, Iveta - Farka, Zdeněk - Pastucha, Matěj - Radoňák, Jozef
PY  - 2020
TI  - Electrochemical determination of insulin at CuNPs/chitosan-MWCNTs and CoNPs/chitosan-MWCNTs modified screen printed carbon electrodes
JF  - Journal of Electroanalytical Chemistry
VL  - 860
IS  - MAR 1 2020
SP  - 1-9
EP  - 1-9
PB  - Elsevier
SN  - 15726657
KW  - Insulin
KW  - Screen printed carbon electrodes
KW  - Copper nanoparticles
KW  - Cobalt nanoparticles
KW  - Electrochemical determination
UR  - https://www.sciencedirect.com/science/article/pii/S1572665720300643
L2  - https://www.sciencedirect.com/science/article/pii/S1572665720300643
N2  - Transition metal nanoparticles can be considered as promising low cost materials for insulin oxidation catalysis. Combination of transition metal nanoparticles with multi walled carbon nanotubes (MWCNTs), which enlarges the active surface area of the electrode, can improve the analytical characteristics of electrodes. Two types of screen printed carbon electrodes (SPCEs) modified by the combination of copper (CuNPs) or cobalt (CoNPs) nanoparticles with chitosan and MWCNTs were prepared. In the effort to find the most suitable modification for electrochemical insulin determination, stability, analytical characteristics and selectivity of both electrode types were compared. The results proved better stability and analytical characteristics with no significant influence of interferences on insulin determination at CoNPs/chitosan-MWCNTs/SPCE. These electrodes provided low limit of detection (25 nM), high sensitivity (0.031 mA uM-1) and wide linear range (0.05 uM to 5 uM) for insulin determination. The stability of the CoNPs/chitosan-MWCNTs/SPCE was very high, with only 1.7% decrease of maximal current value after 50 measurements. Therefore, CoNPs/chitosan-MWCNTs/SPCE can be considered as the suitable modification for new electrochemical sensor for insulin determination, with better analytical characteristics in comparison with SPCE modification using MWCNTs, chitosan and CuNPs described in this study.
ER  -

ŠIŠOLÁKOVÁ, Ivana, Jana HOVANCOVÁ, Renáta ORIŇAKOVÁ, Andrej ORIŇAK, Libuše TRNKOVÁ, Iveta TŘÍSKOVÁ, Zdeněk FARKA, Matěj PASTUCHA and Jozef RADOŇÁK. Electrochemical determination of insulin at CuNPs/chitosan-MWCNTs and CoNPs/chitosan-MWCNTs modified screen printed carbon electrodes. \textit{Journal of Electroanalytical Chemistry}. Lausanne: Elsevier, 2020, vol.~860, MAR 1 2020, p.~1-9. ISSN~1572-6657. Available from: https://dx.doi.org/10.1016/j.jelechem.2020.113881.

Detailed Information on Publication Record