Depth of neuromuscular blockade and the perioperative
conditions in laparoscopic surgery in pediatric population:
Randomized controlled pilot trial

J 2020

Depth of neuromuscular blockade and the perioperative conditions in laparoscopic surgery in pediatric population: Randomized controlled pilot trial

KLUČKA, Jozef, Kateřina SZTURZOVÁ, Martina KOSINOVÁ, Lenka KNOPPOVA, Michaela ŤOUKÁLKOVÁ et. al.

Basic information

Original name

Depth of neuromuscular blockade and the perioperative conditions in laparoscopic surgery in pediatric population: Randomized controlled pilot trial

Authors

KLUČKA, Jozef (703 Slovakia, belonging to the institution), Kateřina SZTURZOVÁ (203 Czech Republic), Martina KOSINOVÁ (203 Czech Republic, guarantor, belonging to the institution), Lenka KNOPPOVA (203 Czech Republic), Michaela ŤOUKÁLKOVÁ (203 Czech Republic, belonging to the institution), Roman ŠTOUDEK (203 Czech Republic, belonging to the institution), Milan KRATOCHVÍL (703 Slovakia, belonging to the institution), Alena TRCKOVA (203 Czech Republic), Martina KLINCOVÁ (703 Slovakia, belonging to the institution), Petra KOVALČÍKOVÁ (203 Czech Republic, belonging to the institution), Tomáš PAVLÍK (203 Czech Republic, belonging to the institution), Ladislav PLÁNKA (203 Czech Republic, belonging to the institution), Jiří TŮMA (203 Czech Republic, belonging to the institution) and Petr ŠTOURAČ (203 Czech Republic, belonging to the institution)

Edition

JOURNAL OF CLINICAL ANESTHESIA, NEW YORK, ELSEVIER SCIENCE INC, 2020, 0952-8180

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30223 Anaesthesiology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 9.452

RIV identification code

RIV/00216224:14110/20:00115320

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.jclinane.2019.109659

UT WoS

000509004000034

Keywords in English

Neuromuscular blockade; Surgical conditions; Laparoscopy; Surgery; Pediatric patient

Abstract

V originále

Neuromuscular blockade (NMB) can facilitate intubation and lead to better intubation and surgical conditions. Preliminary data from the adult population favors the deep NMB for better surgical conditions [1–3], but they are still limited [4]. The primary aim of our trial was to compare surgical conditions during pediatric laparoscopic surgery in subgroups of patients with deep and moderate NMB. The secondary aim was to compare the incidence of complications between the groups. The primary hypothesis was that the deep NMB would lead to superior surgical conditions graded by the surgical scoring system and by the intraperitoneal pressure (lower pressure). This prospective randomized controlled single-blinded pilot study was conducted at a tertiary pediatric anesthesia center after Ethics committee approval (University Hospital in Brno, Czech Republic) and registered at clinicaltrials.gov (NCT02546843).

Links

MUNI/A/0861/2017, interní kód MU

Name: Výskyt obtížné laryngoskopie a obtížného zajištění dýchacích cest v pediatrické anestezii (Difficult airway in paediatric anaesthesia)

Investor: Masaryk University, Category A

MUNI/A/1111/2018, interní kód MU

Name: Videolaryngoskopie vs. přímá laryngoskopie vliv na efektivitu intubace: randomizovaná kontrolovaná studie (Acronym: VidoeLarynx)

Investor: Masaryk University, Category A

ROZV/28/LF8/2020, interní kód MU

Name: Optimalizace periopererační péče u pediatrických pacientů

Investor: Ministry of Education, Youth and Sports of the CR, Internal development projects

ROZV/28/LF9/2020, interní kód MU

Name: Optimalizace periopererační péče u pediatrických pacientů, Časná identifikace sepse, možnosti monitorace a optimalizace hemodynamiky u kriticky nemocného pediatrického pacienta

Investor: Ministry of Education, Youth and Sports of the CR, Internal development projects

Citovat

KLUČKA, Jozef, Kateřina SZTURZOVÁ, Martina KOSINOVÁ, Lenka KNOPPOVA, Michaela ŤOUKÁLKOVÁ, Roman ŠTOUDEK, Milan KRATOCHVÍL, Alena TRCKOVA, Martina KLINCOVÁ, Petra KOVALČÍKOVÁ, Tomáš PAVLÍK, Ladislav PLÁNKA, Jiří TŮMA and Petr ŠTOURAČ. Depth of neuromuscular blockade and the perioperative conditions in laparoscopic surgery in pediatric population: Randomized controlled pilot trial. JOURNAL OF CLINICAL ANESTHESIA. NEW YORK: ELSEVIER SCIENCE INC, 2020, vol. 61, MAY 2020, p. 1-3. ISSN 0952-8180. Available from: https://dx.doi.org/10.1016/j.jclinane.2019.109659.

@article{1621437,
   author = {Klučka, Jozef and Szturzová, Kateřina and Kosinová, Martina and Knoppova, Lenka and Ťoukálková, Michaela and Štoudek, Roman and Kratochvíl, Milan and Trckova, Alena and Klincová, Martina and Kovalčíková, Petra and Pavlík, Tomáš and Plánka, Ladislav and Tůma, Jiří and Štourač, Petr},
   article_location = {NEW YORK},
   article_number = {MAY 2020},
   doi = {http://dx.doi.org/10.1016/j.jclinane.2019.109659},
   keywords = {Neuromuscular blockade; Surgical conditions; Laparoscopy; Surgery; Pediatric patient},
   language = {eng},
   issn = {0952-8180},
   journal = {JOURNAL OF CLINICAL ANESTHESIA},
   title = {Depth of neuromuscular blockade and the perioperative conditions in laparoscopic surgery in pediatric population: Randomized controlled pilot trial},
   url = {http://dx.doi.org/10.1016/j.jclinane.2019.109659},
   volume = {61},
   year = {2020}
}

TY  - JOUR
ID  - 1621437
AU  - Klučka, Jozef - Szturzová, Kateřina - Kosinová, Martina - Knoppova, Lenka - Ťoukálková, Michaela - Štoudek, Roman - Kratochvíl, Milan - Trckova, Alena - Klincová, Martina - Kovalčíková, Petra - Pavlík, Tomáš - Plánka, Ladislav - Tůma, Jiří - Štourač, Petr
PY  - 2020
TI  - Depth of neuromuscular blockade and the perioperative conditions in laparoscopic surgery in pediatric population: Randomized controlled pilot trial
JF  - JOURNAL OF CLINICAL ANESTHESIA
VL  - 61
IS  - MAY 2020
SP  - 1-3
EP  - 1-3
PB  - ELSEVIER SCIENCE INC
SN  - 09528180
KW  - Neuromuscular blockade
KW  - Surgical conditions
KW  - Laparoscopy
KW  - Surgery
KW  - Pediatric patient
UR  - http://dx.doi.org/10.1016/j.jclinane.2019.109659
L2  - http://dx.doi.org/10.1016/j.jclinane.2019.109659
N2  - Neuromuscular blockade (NMB) can facilitate intubation and lead to better intubation and surgical conditions. Preliminary data from the adult population favors the deep NMB for better surgical conditions [1–3], but they are still limited [4]. The primary aim of our trial was to compare surgical conditions during pediatric laparoscopic surgery in subgroups of patients with deep and moderate NMB. The secondary aim was to compare the incidence of complications between the groups. The primary hypothesis was that the deep NMB would lead to superior surgical conditions graded by the surgical scoring system and by the intraperitoneal pressure (lower pressure). This prospective randomized controlled single-blinded pilot study was conducted at a tertiary pediatric anesthesia center after Ethics committee approval (University Hospital in Brno, Czech Republic) and registered at clinicaltrials.gov (NCT02546843).
ER  -

KLUČKA, Jozef, Kateřina SZTURZOVÁ, Martina KOSINOVÁ, Lenka KNOPPOVA, Michaela ŤOUKÁLKOVÁ, Roman ŠTOUDEK, Milan KRATOCHVÍL, Alena TRCKOVA, Martina KLINCOVÁ, Petra KOVALČÍKOVÁ, Tomáš PAVLÍK, Ladislav PLÁNKA, Jiří TŮMA and Petr ŠTOURAČ. Depth of neuromuscular blockade and the perioperative conditions in laparoscopic surgery in pediatric population: Randomized controlled pilot trial. \textit{JOURNAL OF CLINICAL ANESTHESIA}. NEW YORK: ELSEVIER SCIENCE INC, 2020, vol.~61, MAY 2020, p.~1-3. ISSN~0952-8180. Available from: https://dx.doi.org/10.1016/j.jclinane.2019.109659.

Detailed Information on Publication Record