| JURAK, Pavel, Karol CURILA, Pavel LEINVEBER, Frits W. PRINZEN, Ivo VISCOR, Filip PLESINGER, Radovan SMISEK, Radka PROCHAZKOVA, Pavel OSMANCIK, Josef HALAMEK, Magdaléna MATEJKOVÁ, Jolana LIPOLDOVÁ, Miroslav NOVÁK, Roman PANOVSKÝ, Petr ANDRLA, Vlastimil VONDRA, Petr STROS, Jana VESELÁ and Dalibor HERMAN. Novel ultra-high-frequency electrocardiogram tool for the description of the ventricular depolarization pattern before and during cardiac resynchronization. JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY. HOBOKEN: WILEY, 2020, vol. 31, No 1, p. 300-307. ISSN 1045-3873. Available from: https://dx.doi.org/10.1111/jce.14299. |
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@article{1623316,
author = {Jurak, Pavel and Curila, Karol and Leinveber, Pavel and Prinzen, Frits W. and Viscor, Ivo and Plesinger, Filip and Smisek, Radovan and Prochazkova, Radka and Osmancik, Pavel and Halamek, Josef and Matejková, Magdaléna and Lipoldová, Jolana and Novák, Miroslav and Panovský, Roman and Andrla, Petr and Vondra, Vlastimil and Stros, Petr and Veselá, Jana and Herman, Dalibor},
article_location = {HOBOKEN},
article_number = {1},
doi = {http://dx.doi.org/10.1111/jce.14299},
keywords = {biventricular pacing; cardiac resynchronization therapy; His-bundle pacing; ultra-high-frequency ECG; ventricular electrical dyssynchrony},
language = {eng},
issn = {1045-3873},
journal = {JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY},
title = {Novel ultra-high-frequency electrocardiogram tool for the description of the ventricular depolarization pattern before and during cardiac resynchronization},
url = {http://dx.doi.org/10.1111/jce.14299},
volume = {31},
year = {2020}
}
TY - JOUR
ID - 1623316
AU - Jurak, Pavel - Curila, Karol - Leinveber, Pavel - Prinzen, Frits W. - Viscor, Ivo - Plesinger, Filip - Smisek, Radovan - Prochazkova, Radka - Osmancik, Pavel - Halamek, Josef - Matejková, Magdaléna - Lipoldová, Jolana - Novák, Miroslav - Panovský, Roman - Andrla, Petr - Vondra, Vlastimil - Stros, Petr - Veselá, Jana - Herman, Dalibor
PY - 2020
TI - Novel ultra-high-frequency electrocardiogram tool for the description of the ventricular depolarization pattern before and during cardiac resynchronization
JF - JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
VL - 31
IS - 1
SP - 300-307
EP - 300-307
PB - WILEY
SN - 10453873
KW - biventricular pacing
KW - cardiac resynchronization therapy
KW - His-bundle pacing
KW - ultra-high-frequency ECG
KW - ventricular electrical dyssynchrony
UR - http://dx.doi.org/10.1111/jce.14299
L2 - http://dx.doi.org/10.1111/jce.14299
N2 - Introduction The present study introduces a new ultra-high-frequency 14-lead electrocardiogram technique (UHF-ECG) for mapping ventricular depolarization patterns and calculation of novel dyssynchrony parameters that may improve the selection of patients and application of cardiac resynchronization therapy (CRT). Methods Components of the ECG in sixteen frequency bands within the 150 to 1000 Hz range were used to create ventricular depolarization maps. The maximum time difference between the UHF QRS complex centers of mass of leads V1 to V8 was defined as ventricular electrical dyssynchrony (e-DYS), and the duration at 50% of peak voltage amplitude in each lead was defined as the duration of local depolarization (Vd). Proof of principle measurements was performed in seven patients with left (left bundle branch block) and four patients with right bundle branch block (right bundle branch block) before and during CRT using biventricular and His-bundle pacing. Results The acquired activation maps reflect the activation sequence under the tested conditions. e-DYS decreased considerably more than QRS duration, during both biventricular pacing (-50% vs -8%) and His-bundle pacing (-77% vs -13%). While biventricular pacing slightly increased Vd, His-bundle pacing reduced Vd significantly (+11% vs -36%), indicating the contribution of the fast conduction system. Optimization of biventricular pacing by adjusting VV-interval showed a decrease of e-DYS from 102 to 36 ms with only a small Vd increase and QRS duration decrease. Conclusions The UHF-ECG technique provides novel information about electrical activation of the ventricles from a standard ECG electrode setup, potentially improving the selection of patients for CRT and application of CRT.
ER -
JURAK, Pavel, Karol CURILA, Pavel LEINVEBER, Frits W. PRINZEN, Ivo VISCOR, Filip PLESINGER, Radovan SMISEK, Radka PROCHAZKOVA, Pavel OSMANCIK, Josef HALAMEK, Magdaléna MATEJKOVÁ, Jolana LIPOLDOVÁ, Miroslav NOVÁK, Roman PANOVSKÝ, Petr ANDRLA, Vlastimil VONDRA, Petr STROS, Jana VESELÁ and Dalibor HERMAN. Novel ultra-high-frequency electrocardiogram tool for the description of the ventricular depolarization pattern before and during cardiac resynchronization. \textit{JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY}. HOBOKEN: WILEY, 2020, vol.~31, No~1, p.~300-307. ISSN~1045-3873. Available from: https://dx.doi.org/10.1111/jce.14299.
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