J 2020

Erectile Dysfunction Treatment Using Focused Linear Low-Intensity Extracorporeal Shockwaves: Single-Blind, Sham-Controlled, Randomized Clinical Trial

ŠRÁMKOVÁ, Taťána, Igor MOTIL, Jiří JARKOVSKÝ and Kateřina ŠRÁMKOVÁ

Basic information

Original name

Erectile Dysfunction Treatment Using Focused Linear Low-Intensity Extracorporeal Shockwaves: Single-Blind, Sham-Controlled, Randomized Clinical Trial

Authors

ŠRÁMKOVÁ, Taťána (203 Czech Republic, guarantor, belonging to the institution), Igor MOTIL (203 Czech Republic), Jiří JARKOVSKÝ (203 Czech Republic, belonging to the institution) and Kateřina ŠRÁMKOVÁ (203 Czech Republic)

Edition

Urologia Internationalis, Basel, Karger, 2020, 0042-1138

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30217 Urology and nephrology

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 2.089

RIV identification code

RIV/00216224:14110/20:00115341

Organization unit

Faculty of Medicine

DOI

UT WoS

000543544500014

Keywords in English

Erectile dysfunction; Cardiovascular disease; Low-intensity extracorporeal shockwave; Phosphodiesterase-5 inhibitors

Tags

Tags

International impact, Reviewed
Změněno: 31/8/2020 12:18, Mgr. Tereza Miškechová

Abstract

V originále

Introduction:Low-intensity extracorporeal shock wave therapy (Li-ESWT) is a new treatment modality for erectile dysfunction (ED). Our aim was to evaluate the treatment outcome of Li-ESWT for ED in single-blind, placebo controlled, randomized clinical trial.Methods:Sixty patients were randomized into 2 age-matched groups: Group A - treatment and Group B - placebo. Treatment consisted of 4 sessions on the PiezoWave2 unit (R. Wolf and ELvation Medical). Effectiveness was assessed according to the International Index of Erectile Function 5 (IIEF-5), Erectile Hardness Score (EHS), questions 2 and 3 of the Sexual Encounter Profile (SEP 2, SEP 3), and Global Assessment Question (GAQ) scores at baseline and 4 and 12 weeks after treatment. We evaluated patient's and partner's subjective satisfaction.Results:A statistically significant difference between the groups was found at 4 and 12 weeks after treatment with regard to the quality of erection as measured by the IIEF-5 (p= 0.049 andp< 0.001, respectively), the EHS after week 12 (p< 0.001), an increase in the EHS after 4 and 12 weeks (p= 0.030 andp< 0.001, respectively), after 12 weeks in GAQ (p< 0.001), SEP 2 (p= 0.05), SEP 3 (p< 0.001), and patient's satisfaction (p< 0.001) and partner's satisfaction (p< 0.001).Conclusions:The randomized single-blind study confirms that Li-ESWT significantly improves erectile function.