| ČUTOVÁ, Michaela, Jacinta MANTA, Otília PORUBIAKOVÁ, Patrik KAURA, Jiří ŠŤASTNÝ, Eva B. JAGELSKÁD, Pratik GOSWAMI, Martin BARTAS and Václav BRÁZDA. Divergent distributions of inverted repeats and G-quadruplex forming sequences in Saccharomyces cerevisiae. Genomics. United States: Elsevier Science Inc, 2020, vol. 112, No 2, p. 1897-1901. ISSN 0888-7543. Available from: https://dx.doi.org/10.1016/j.ygeno.2019.11.002. |
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@article{1624756,
author = {Čutová, Michaela and Manta, Jacinta and Porubiaková, Otília and Kaura, Patrik and Šťastný, Jiří and Jagelskád, Eva B. and Goswami, Pratik and Bartas, Martin and Brázda, Václav},
article_location = {United States},
article_number = {2},
doi = {http://dx.doi.org/10.1016/j.ygeno.2019.11.002},
keywords = {G-quadruplex; Inverted repeat; Saccharomyces cerevisiae},
issn = {0888-7543},
journal = {Genomics},
note = {Žádný z autorů nemá afiliaci k MU. Nevykazovat do RIV.},
title = {Divergent distributions of inverted repeats and G-quadruplex forming sequences in Saccharomyces cerevisiae},
url = {https://www.sciencedirect.com/science/article/pii/S0888754319305269},
volume = {112},
year = {2020}
}
TY - JOUR
ID - 1624756
AU - Čutová, Michaela - Manta, Jacinta - Porubiaková, Otília - Kaura, Patrik - Šťastný, Jiří - Jagelskád, Eva B. - Goswami, Pratik - Bartas, Martin - Brázda, Václav
PY - 2020
TI - Divergent distributions of inverted repeats and G-quadruplex forming sequences in Saccharomyces cerevisiae
JF - Genomics
VL - 112
IS - 2
SP - 1897-1901
EP - 1897-1901
PB - Elsevier Science Inc
SN - 08887543
N1 - Žádný z autorů nemá afiliaci k MU. Nevykazovat do RIV.
KW - G-quadruplex
KW - Inverted repeat
KW - Saccharomyces cerevisiae
UR - https://www.sciencedirect.com/science/article/pii/S0888754319305269
N2 - The importance of DNA structure in the regulation of basic cellular processes is an emerging field of research. Among local non-B DNA structures, inverted repeat (IR) sequences that form cruciforms and G-rich sequences that form G-quadruplexes (G4) are found in all prokaryotic and eukaryotic organisms and are targets for regulatory proteins. We analyzed IRs and G4 sequences in the genome of the most important biotechnology microorganism, S. cerevisiae. IR and G4-prone sequences are enriched in specific genomic locations and differ markedly between mitochondrial and nuclear DNA. While G4s are overrepresented in telomeres and regions surrounding tRNAs, IRs are most enriched in centromeres, rDNA, replication origins and surrounding tRNAs. Mitochondrial DNA is enriched in both IR and G4-prone sequences relative to the nuclear genome. This extensive analysis of local DNA structures adds to the emerging picture of their importance in genome maintenance, DNA replication and transcription of subsets of genes.
ER -
ČUTOVÁ, Michaela, Jacinta MANTA, Otília PORUBIAKOVÁ, Patrik KAURA, Jiří ŠŤASTNÝ, Eva B. JAGELSKÁD, Pratik GOSWAMI, Martin BARTAS and Václav BRÁZDA. Divergent distributions of inverted repeats and G-quadruplex forming sequences in Saccharomyces cerevisiae. \textit{Genomics}. United States: Elsevier Science Inc, 2020, vol.~112, No~2, p.~1897-1901. ISSN~0888-7543. Available from: https://dx.doi.org/10.1016/j.ygeno.2019.11.002.
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