KLESCHENKO, Y., Danyil GRYBCHUK, N.S. MATVEEVA, D.H. MACEDO, E.N. PONIROVSKY, A.N. LUKASHEV and V. YURCHENKO. Molecular Characterization of Leishmania RNA virus 2 in Leishmania major from Uzbekistan. Genes. Basilej: MDPI, 2019, vol. 10, No 10, p. 1-10. ISSN 2073-4425. Available from: https://dx.doi.org/10.3390/genes10100830.
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Basic information
Original name Molecular Characterization of Leishmania RNA virus 2 in Leishmania major from Uzbekistan
Authors KLESCHENKO, Y., Danyil GRYBCHUK (804 Ukraine, guarantor, belonging to the institution), N.S. MATVEEVA, D.H. MACEDO, E.N. PONIROVSKY, A.N. LUKASHEV and V. YURCHENKO.
Edition Genes, Basilej, MDPI, 2019, 2073-4425.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10603 Genetics and heredity
Country of publisher Switzerland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.759
RIV identification code RIV/00216224:14740/19:00113264
Organization unit Central European Institute of Technology
Doi http://dx.doi.org/10.3390/genes10100830
UT WoS 000498397100101
Keywords in English Leishmania RNA virus; next-generation sequencing; LRV2
Tags rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Pavla Foltynová, Ph.D., učo 106624. Changed: 16/3/2020 10:58.
Abstract
Here we report sequence and phylogenetic analysis of two new isolates of Leishmania RNA virus 2 (LRV2) found in Leishmania major isolated from human patients with cutaneous leishmaniasis in south Uzbekistan. These new virus-infected flagellates were isolated in the same region of Uzbekistan and the viral sequences differed by only nineteen SNPs, all except one being silent mutations. Therefore, we concluded that they belong to a single LRV2 species. New viruses are closely related to the LRV2-Lmj-ASKH documented in Turkmenistan in 1995, which is congruent with their shared host (L. major) and common geographical origin.
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