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@article{1637476,
author = {Louis, Elan D. and Bareš, Martin and BenitoandLeon, Julian and Fahn, Stanley and Frucht, Steven J. and Jankovic, Joseph and Ondo, William G. and Pal, Pramod K. and Tan, EngandKing},
article_location = {London, UK},
article_number = {3},
doi = {http://dx.doi.org/10.1016/S1474-4422(19)30398-9},
keywords = {CONSENSUS STATEMENT; HEAD TREMOR; DISORDER; DYSTONIA; PREVALENCE; DEMENTIA; NETWORK; DECLINE; DISEASE},
language = {eng},
issn = {1474-4422},
journal = {Lancet Neurology},
title = {Essential tremor-plus: a controversial new concept},
url = {http://dx.doi.org/10.1016/S1474-4422(19)30398-9},
volume = {19},
year = {2020}
}
TY - JOUR
ID - 1637476
AU - Louis, Elan D. - Bareš, Martin - Benito-Leon, Julian - Fahn, Stanley - Frucht, Steven J. - Jankovic, Joseph - Ondo, William G. - Pal, Pramod K. - Tan, Eng-King
PY - 2020
TI - Essential tremor-plus: a controversial new concept
JF - Lancet Neurology
VL - 19
IS - 3
SP - 266-270
EP - 266-270
PB - Elsevier
SN - 14744422
KW - CONSENSUS STATEMENT
KW - HEAD TREMOR
KW - DISORDER
KW - DYSTONIA
KW - PREVALENCE
KW - DEMENTIA
KW - NETWORK
KW - DECLINE
KW - DISEASE
UR - http://dx.doi.org/10.1016/S1474-4422(19)30398-9
L2 - http://dx.doi.org/10.1016/S1474-4422(19)30398-9
N2 - In addition to redefining essential tremor (ET), the 2018 consensus statement of the Movement Disorder Society on tremor coined a new term: essential tremor-plus (ET-plus). This term is uncertainly defined as tremor with the characteristics of ET, with additional neurological signs of uncertain clinical significance. If ET-plus had been defined on the basis of a difference in underlying pathology or an appreciable difference in prognosis, it would have a valid, scientific rationale, as does the term Parkinson-plus. However, there is no such evidence, so the basis for the term is questionable. In fact, ET-plus might only represent a state condition (ie, patients with ET might develop these additional clinical features when the disease is at a more advanced stage). We caution against coining new terms that are not supported by a firm scientific basis and encourage research into the creation of essential tremor subsets that are defined with respect to differences in underlying causes or pathophysiology.
ER -
LOUIS, Elan D., Martin BAREŠ, Julian BENITO-LEON, Stanley FAHN, Steven J. FRUCHT, Joseph JANKOVIC, William G. ONDO, Pramod K. PAL and Eng-King TAN. Essential tremor-plus: a controversial new concept. \textit{Lancet Neurology}. London, UK: Elsevier, 2020, vol.~19, No~3, p.~266-270. ISSN~1474-4422. Available from: https://dx.doi.org/10.1016/S1474-4422(19)30398-9.
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