J 2020

Recombinant human C1 esterase inhibitor as short-term prophylaxis in patients with hereditary angioedema

VALERIEVA, Anna, Maria STAEVSKA, Milos JESENAK, Katarina HRUBISKOVA, Marta SOBOTKOVA et. al.

Basic information

Original name

Recombinant human C1 esterase inhibitor as short-term prophylaxis in patients with hereditary angioedema

Authors

VALERIEVA, Anna (100 Bulgaria, guarantor), Maria STAEVSKA (100 Bulgaria), Milos JESENAK (703 Slovakia), Katarina HRUBISKOVA (703 Slovakia), Marta SOBOTKOVA (203 Czech Republic), Radana ZACHOVA (203 Czech Republic), Roman HAKL (203 Czech Republic, belonging to the institution), Sladjana ANDREJEVIC (688 Serbia), Tobias SUITER (528 Netherlands), Vesna GRIVCHEVA-PANOVSKA (807 North Macedonia), Ljerka KARADZA-LAPIC (191 Croatia), Daniel SOTERES (840 United States of America), Ralph SHAPIRO (840 United States of America), Jeffrey RUMBYRT (840 United States of America), Raffi TACHDJIAN (840 United States of America), Vinay MEHTA (840 United States of America), F. Ida HSU (840 United States of America) and Andrea ZANICHELLI (380 Italy)

Edition

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, AMSTERDAM, ELSEVIER, 2020, 2213-2198

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30102 Immunology

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 8.861

RIV identification code

RIV/00216224:14110/20:00115435

Organization unit

Faculty of Medicine

UT WoS

000512964500062

Keywords in English

C1-INHIBITOR; ATTACKS; DEFICIENCY; EFFICACY

Tags

Tags

International impact, Reviewed
Změněno: 12/5/2021 12:56, Mgr. Tereza Miškechová

Abstract

V originále

Hereditary angioedema (HAE), an inherited deficiency offunctional C1 esterase inhibitor (C1-INH), is characterized byrecurrent episodes of disabling and often painful swelling insubcutaneous and/or submucosal tissues.1HAE attacks aregenerally unpredictable, but triggers for an attack can includehaving a dental or medical procedure (eg, surgery), other trauma,or stress. A preemptive management plan for patients under-going these types of situations may reduce the risk of HAE at-tacks. Recommendations include administration of short-termprophylaxis in patients with HAE before invasive medical pro-cedures, especially those involving the upper airways or digestivetract, with C1-INH concentrate typically the medication ofchoice.