Detailed Information on Publication Record
2019
Investigation of microRNA expression profiles related tomorphological heterogeneity in triple-negative breast cancer
KOLECKOVA, M., Z. KOLAR, J. EHRMANN, Marek SVOBODA, Ondřej SLABÝ et. al.Basic information
Original name
Investigation of microRNA expression profiles related tomorphological heterogeneity in triple-negative breast cancer
Authors
KOLECKOVA, M., Z. KOLAR, J. EHRMANN, Marek SVOBODA (203 Czech Republic, belonging to the institution), Ondřej SLABÝ (203 Czech Republic, belonging to the institution), J. BOUCHAL, K. BOUCHALOVA, M. JANIKOVA, J. SROVNAL and Lenka RADOVÁ (203 Czech Republic, guarantor, belonging to the institution)
Edition
VIRCHOWS ARCHIV, 2019
Other information
Language
English
Type of outcome
Konferenční abstrakt
Field of Study
30204 Oncology
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
RIV identification code
RIV/00216224:14740/19:00108611
Organization unit
Central European Institute of Technology
UT WoS
000483546900052
Keywords in English
microRNA; breast cancer
Tags
Tags
International impact
Změněno: 29/3/2020 20:48, Mgr. Pavla Foltynová, Ph.D.
Abstract
V originále
: Triple-negative breast cancers (TNBCs) are morphologically a heterogeneous group of breast carcinomas with no or minimal hormone receptor and HER2 protein expression or gene amplification. Due to its aggressive nature, novel therapeutic targets are urgently required to improve pathological complete response and clinical outcomes. In tumours, microRNAs (miRs) exhibit both oncogenic and tumour-supressor function. The aim of this study was to indentify a possible association between miRs expression profile and intratumoural morphology within different samples of TNBC.
Links
| NV16-31997A, research and development project |
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