Detailed Information on Publication Record
2019
Dysregulated expression of lncRNAs in glioblastoma multiforme and their association with overall survival
VEČEŘA, Marek, Jan OPPELT, Lenka RADOVÁ, Radim LIPINA, S. REGULI et. al.Basic information
Original name
Dysregulated expression of lncRNAs in glioblastoma multiforme and their association with overall survival
Authors
VEČEŘA, Marek (703 Slovakia, belonging to the institution), Jan OPPELT (203 Czech Republic, belonging to the institution), Lenka RADOVÁ (203 Czech Republic, belonging to the institution), Radim LIPINA (203 Czech Republic, belonging to the institution), S. REGULI, Martin SMRČKA (203 Czech Republic, belonging to the institution), R. JANCALEK, M. FILIP, M. HERMANOVA, L. KREN, Jiří ŠÁNA (203 Czech Republic, belonging to the institution), Alena KOPKOVÁ (203 Czech Republic, belonging to the institution), Júlia BOHOŠOVÁ (703 Slovakia, belonging to the institution) and Ondřej SLABÝ (203 Czech Republic, guarantor, belonging to the institution)
Edition
Annual Meeting of the American-Association-for-Cancer-Research (AACR), 2019
Other information
Language
English
Type of outcome
Konferenční abstrakt
Field of Study
30204 Oncology
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
RIV identification code
RIV/00216224:14740/19:00108217
Organization unit
Central European Institute of Technology
UT WoS
000488279402481
Keywords in English
lncRNAs; glioblastoma
Tags
Tags
International impact
Změněno: 3/4/2020 19:53, Mgr. Pavla Foltynová, Ph.D.
Abstract
V originále
Glioblastoma multiforme (GBM) is the most frequent primary brain malignancy of astrocytic origin. The prognosis remains very poor with the median overall survival (OS) being between 12 and 16 months from diagnosis despite early use of conventional medical therapy. Identifying new therapeutic targets, as well as prognostic and predictive biomarkers for accurate stratification of patients is therefore of utmost importance. Long non-coding RNAs (lncRNAs) are regulators of gene expression having critical impact on both physiological processes and the molecular pathology of GBM, indicating their potential as biomarkers and therapeutic targets.
Links
| GA17-17636S, research and development project |
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| LQ1601, research and development project |
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| NV18-03-00398, research and development project |
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