| ŘEHÁKOVÁ, Daniela, Tereza SOURALOVÁ a Irena KOUTNÁ. Clinical-Grade Human Pluripotent Stem Cells for Cell Therapy: Characterization Strategy. International Journal of Molecular Sciences. Basel: MDPI, 2020, roč. 21, č. 7, s. 1-14. ISSN 1422-0067. Dostupné z: https://dx.doi.org/10.3390/ijms21072435. |
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@article{1641416,
author = {Řeháková, Daniela and Souralová, Tereza and Koutná, Irena},
article_location = {Basel},
article_number = {7},
doi = {http://dx.doi.org/10.3390/ijms21072435},
keywords = {hPSCs; human pluripotent stem cells; characterization; hESC; human embryonic stem cells; hiPSC; human induced pluripotent stem cells; clinical; cGMP; cell therapy},
language = {eng},
issn = {1422-0067},
journal = {International Journal of Molecular Sciences},
title = {Clinical-Grade Human Pluripotent Stem Cells for Cell Therapy: Characterization Strategy},
url = {https://www.mdpi.com/1422-0067/21/7/2435},
volume = {21},
year = {2020}
}
TY - JOUR
ID - 1641416
AU - Řeháková, Daniela - Souralová, Tereza - Koutná, Irena
PY - 2020
TI - Clinical-Grade Human Pluripotent Stem Cells for Cell Therapy: Characterization Strategy
JF - International Journal of Molecular Sciences
VL - 21
IS - 7
SP - 1-14
EP - 1-14
PB - MDPI
SN - 14220067
KW - hPSCs
KW - human pluripotent stem cells
KW - characterization
KW - hESC
KW - human embryonic stem cells
KW - hiPSC
KW - human induced pluripotent stem cells
KW - clinical
KW - cGMP
KW - cell therapy
UR - https://www.mdpi.com/1422-0067/21/7/2435
L2 - https://www.mdpi.com/1422-0067/21/7/2435
N2 - Human pluripotent stem cells have the potential to change the way in which human diseases are cured. Clinical-grade human embryonic stem cells and human induced pluripotent stem cells have to be created according to current good manufacturing practices and regulations. Quality and safety must be of the highest importance when humans' lives are at stake. With the rising number of clinical trials, there is a need for a consensus on hPSCs characterization. Here, we summarize mandatory and ' for information only ' characterization methods with release criteria for the establishment of clinical-grade hPSC lines.
ER -
ŘEHÁKOVÁ, Daniela, Tereza SOURALOVÁ a Irena KOUTNÁ. Clinical-Grade Human Pluripotent Stem Cells for Cell Therapy: Characterization Strategy. \textit{International Journal of Molecular Sciences}. Basel: MDPI, 2020, roč.~21, č.~7, s.~1-14. ISSN~1422-0067. Dostupné z: https://dx.doi.org/10.3390/ijms21072435.
|
