Identifying urinary microRNAs for heart allograft rejection
monitoring using small RNA sequencing - Pilot results

a 2019

Identifying urinary microRNAs for heart allograft rejection monitoring using small RNA sequencing - Pilot results

NOVÁK, Jan, Táňa MACHÁČKOVÁ, Tereza NOVÁKOVÁ, Július GODAVA, Petr HUDE et. al.

Basic information

Original name

Identifying urinary microRNAs for heart allograft rejection monitoring using small RNA sequencing - Pilot results

Authors

NOVÁK, Jan (203 Czech Republic, belonging to the institution), Táňa MACHÁČKOVÁ (203 Czech Republic, belonging to the institution), Tereza NOVÁKOVÁ (203 Czech Republic, belonging to the institution), Július GODAVA (703 Slovakia), Petr HUDE (203 Czech Republic), Víta ŽAMPACHOVÁ (203 Czech Republic), Jan OPPELT (203 Czech Republic, belonging to the institution), Petr NĚMEC (203 Czech Republic), Helena BEDÁŇOVÁ (203 Czech Republic), Ondřej SLABÝ (203 Czech Republic, guarantor, belonging to the institution), Julie DOBROVOLNÁ (203 Czech Republic, belonging to the institution), Jan KREJČÍ (203 Czech Republic) and Lenka ŠPINAROVÁ (203 Czech Republic)

Edition

ESC365, 2019

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 11.627

RIV identification code

RIV/00216224:14740/19:00108615

Organization unit

Central European Institute of Technology

ISSN

UT WoS

000468990703267

Keywords in English

urinary microRNAs

Abstract

V originále

Heart failure (HF) represents one of the leading causes of death in the developed countries and heart transplantation (HT) is the only solution for patients with terminal refractory HF. Patients after HT are at risk of acute cellular rejection (ACR) potentially causing graft damage and failure. Diagnostics of ACR is based on histopathologic evaluation of endomyocardial biopsies (EMB) as no non-invasive biomarker has been found yet. microRNAs (miRNAs, miRs) are tiny non-coding RNA molecules involved in post-transcriptional regulation of gene expression. Extracellularly they are potentially involved in intercellular communication and because of their high stability they represent novel potential biomarkers.

Links

NV16-30537A, research and development project

Name: Cirkulující mikroRNA jako neinvazivní markery rejekce štěpu u pacientů po srdeční transplantaci

Citovat

NOVÁK, Jan, Táňa MACHÁČKOVÁ, Tereza NOVÁKOVÁ, Július GODAVA, Petr HUDE, Víta ŽAMPACHOVÁ, Jan OPPELT, Petr NĚMEC, Helena BEDÁŇOVÁ, Ondřej SLABÝ, Julie DOBROVOLNÁ, Jan KREJČÍ and Lenka ŠPINAROVÁ. Identifying urinary microRNAs for heart allograft rejection monitoring using small RNA sequencing - Pilot results. In ESC365. 2019. ISSN 1388-9842.

@proceedings{1641757,
   author = {Novák, Jan and Macháčková, Táňa and Nováková, Tereza and Godava, Július and Hude, Petr and Žampachová, Víta and Oppelt, Jan and Němec, Petr and Bedáňová, Helena and Slabý, Ondřej and Dobrovolná, Julie and Krejčí, Jan and Špinarová, Lenka},
   booktitle = {ESC365},
   keywords = {urinary microRNAs},
   language = {eng},
   title = {Identifying urinary microRNAs for heart allograft rejection monitoring using small RNA sequencing - Pilot results},
   year = {2019}
}

TY  - CONF
ID  - 1641757
AU  - Novák, Jan - Macháčková, Táňa - Nováková, Tereza - Godava, Július - Hude, Petr - Žampachová, Víta - Oppelt, Jan - Němec, Petr - Bedáňová, Helena - Slabý, Ondřej - Dobrovolná, Julie - Krejčí, Jan - Špinarová, Lenka
PY  - 2019
TI  - Identifying urinary microRNAs for heart allograft rejection monitoring using small RNA sequencing - Pilot results
KW  - urinary microRNAs
N2  - Heart failure (HF) represents one of the leading causes of death in the developed countries and heart transplantation (HT) is the only solution for patients with terminal refractory HF. Patients after HT are at risk of acute cellular rejection (ACR) potentially causing graft damage and failure. Diagnostics of ACR is based on histopathologic evaluation of endomyocardial biopsies (EMB) as no non-invasive biomarker has been found yet. microRNAs (miRNAs, miRs) are tiny non-coding RNA molecules involved in post-transcriptional regulation of gene expression. Extracellularly they are potentially involved in intercellular communication and because of their high stability they represent novel potential biomarkers.
ER  -

Detailed Information on Publication Record