VAN EIMEREN, T., A. ANTONINI, D. BERG, N. BOHNEN, R. CERAVOLO, A. DRZEZGA, G. HÖGLINGER, M. HIGUCHI, S. LEHERICY, S. LEWIS, O. MONCHI, P. NESTOR, M. ONDRUS, N. PAVESE, M.C. PERALTA, P. PICCINI, J.A. PINEDA-PARDO, Irena REKTOROVÁ and M. RODRÍGUEZ-OROZ. Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. Elsevier, 2019, vol. 11, No 2019, p. 301-309. ISSN 2352-8729. Available from: https://dx.doi.org/10.1016/j.dadm.2019.01.011.
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Basic information
Original name Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System
Authors VAN EIMEREN, T., A. ANTONINI, D. BERG, N. BOHNEN, R. CERAVOLO, A. DRZEZGA, G. HÖGLINGER, M. HIGUCHI, S. LEHERICY, S. LEWIS, O. MONCHI, P. NESTOR, M. ONDRUS, N. PAVESE, M.C. PERALTA, P. PICCINI, J.A. PINEDA-PARDO, Irena REKTOROVÁ (203 Czech Republic, guarantor, belonging to the institution) and M. RODRÍGUEZ-OROZ.
Edition Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, Elsevier, 2019, 2352-8729.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30210 Clinical neurology
Country of publisher Netherlands
Confidentiality degree is not subject to a state or trade secret
WWW URL
RIV identification code RIV/00216224:14740/19:00113539
Organization unit Central European Institute of Technology
Doi http://dx.doi.org/10.1016/j.dadm.2019.01.011
UT WoS 000723892800035
Keywords in English Biomarker; CDB; CBS; MRI;MSA
Tags rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Pavla Foltynová, Ph.D., učo 106624. Changed: 6/4/2020 18:30.
Abstract
Therapeutic strategies targeting protein aggregations are ready for clinical trials in atypical parkinsonian disorders. Therefore, there is an urgent need for neuroimaging biomarkers to help with the early detection of neurodegenerative processes, the early differentiation of the underlying pathology, and the objective assessment of disease progression. However, there currently is not yet a consensus in the field on how to describe utility of biomarkers for clinical trials in atypical parkinsonian disorders.
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