Detailed Information on Publication Record
2019
MicroRNA analysis in multiple myeloma and extramedullary disease
GREGOROVÁ, Jana, Lenka RADOVÁ, Natalia Anna GABŁO, M. ALMASI, M. STORK et. al.Basic information
Original name
MicroRNA analysis in multiple myeloma and extramedullary disease
Authors
GREGOROVÁ, Jana (203 Czech Republic, belonging to the institution), Lenka RADOVÁ (203 Czech Republic, belonging to the institution), Natalia Anna GABŁO (616 Poland, belonging to the institution), M. ALMASI, M. STORK, Ondřej SLABÝ (203 Czech Republic, belonging to the institution), L. POUR, J. MINARIK and Sabina ŠEVČÍKOVÁ (203 Czech Republic, guarantor, belonging to the institution)
Edition
17th International Myeloma Workshop, 2019
Other information
Language
English
Type of outcome
Konferenční abstrakt
Field of Study
30204 Oncology
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 2.298
RIV identification code
RIV/00216224:14110/19:00108621
Organization unit
Faculty of Medicine
ISSN
UT WoS
000491229800102
Keywords in English
extramedullary disease; microRNA; Next Generation Sequencing
Tags
Tags
International impact
Změněno: 3/4/2020 19:50, Mgr. Pavla Foltynová, Ph.D.
Abstract
V originále
MicroRNAs (miRNAs) are short non-coding RNA molecules that are involved in many physiological and pathological processes. Multiple myeloma (MM) is the second most common hematological malignancy of plasma cells (PCs). Survival of patients is negatively affected by extramedullary disease (EM). EM occurs when PCs migrate out of the bone marrow (BM) and lose the dependence to its microenvironment. The mechanism by which the EM occurs is not yet elucidated. The importance of miRNA in the pathogenesis of MM has been demonstrated by several studies. We assume that they are involved in the development of EM. Aims: The aim of this work was to analyze different expression of miRNA in BM PCs of EM vs MM patients.
Links
| NV17-29343A, research and development project |
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