MAKHNEVA, Ekaterina, Laura BARILLAS, Zdeněk FARKA, Matěj PASTUCHA, Petr SKLÁDAL, Klaus-Dieter WELTMANN and Katja FRICKE. Functional Plasma Polymerized Surfaces for Biosensing. ACS Applied Materials & Interfaces. Washington, DC: American Chemical Society, 2020, vol. 12, No 14, p. 17100-17112. ISSN 1944-8244. Available from: https://dx.doi.org/10.1021/acsami.0c01443.
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Basic information
Original name Functional Plasma Polymerized Surfaces for Biosensing
Authors MAKHNEVA, Ekaterina (643 Russian Federation), Laura BARILLAS, Zdeněk FARKA (203 Czech Republic, belonging to the institution), Matěj PASTUCHA (203 Czech Republic, belonging to the institution), Petr SKLÁDAL (203 Czech Republic, guarantor, belonging to the institution), Klaus-Dieter WELTMANN and Katja FRICKE.
Edition ACS Applied Materials & Interfaces, Washington, DC, American Chemical Society, 2020, 1944-8244.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10305 Fluids and plasma physics
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 9.229
RIV identification code RIV/00216224:14740/20:00115502
Organization unit Central European Institute of Technology
Doi http://dx.doi.org/10.1021/acsami.0c01443
UT WoS 000526583500119
Keywords in English atmospheric-pressure plasma-induced polymerization; functional polymers; chemical composition; thin films; biosensing
Tags CF NANO, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Pavla Foltynová, Ph.D., učo 106624. Changed: 1/3/2021 19:04.
Abstract
The capabilities of biosensors for fast, economic, and user-friendly analysis of complex samples has led to the exploitation of analytical devices for detection, quantification, and monitoring of specific chemical species for various applications. For a sufficiently high surface reactivity toward the adopted bioreceptors, a thin functional layer is required to enable coupling of the target biomolecules and to provide good stability in the presence of a sample matrix. In this work, the generation of water-stable oxygen-rich plasma polymerized (pp) films deposited by atmospheric-pressure jet plasma for reliable immobilization of biomolecules is presented. Three types of pp films were developed and characterized. All of the obtained pp films were successfully used as a matrix layer in the SPR immunosensors, which provided excellent level of sensitivity, stability, and regenerability. The achieved results show that atmospheric pressure plasma-induced polymerization is a powerful alternative method for the preparation of matrix layers for a wide range of applications in the biological field.
Links
LM2018127, research and development projectName: Česká infrastruktura pro integrativní strukturní biologii (Acronym: CIISB)
Investor: Ministry of Education, Youth and Sports of the CR
LQ1601, research and development projectName: CEITEC 2020 (Acronym: CEITEC2020)
Investor: Ministry of Education, Youth and Sports of the CR
MUNI/A/1252/2019, interní kód MUName: Podpora biochemického výzkumu v roce 2020
Investor: Masaryk University, Category A
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