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@article{1644003, author = {Makhneva, Ekaterina and Barillas, Laura and Farka, Zdeněk and Pastucha, Matěj and Skládal, Petr and Weltmann, KlausandDieter and Fricke, Katja}, article_location = {Washington, DC}, article_number = {14}, doi = {http://dx.doi.org/10.1021/acsami.0c01443}, keywords = {atmospheric-pressure plasma-induced polymerization; functional polymers; chemical composition; thin films; biosensing}, language = {eng}, issn = {1944-8244}, journal = {ACS Applied Materials & Interfaces}, title = {Functional Plasma Polymerized Surfaces for Biosensing}, url = {https://pubs.acs.org/doi/10.1021/acsami.0c01443}, volume = {12}, year = {2020} }
TY - JOUR ID - 1644003 AU - Makhneva, Ekaterina - Barillas, Laura - Farka, Zdeněk - Pastucha, Matěj - Skládal, Petr - Weltmann, Klaus-Dieter - Fricke, Katja PY - 2020 TI - Functional Plasma Polymerized Surfaces for Biosensing JF - ACS Applied Materials & Interfaces VL - 12 IS - 14 SP - 17100-17112 EP - 17100-17112 PB - American Chemical Society SN - 19448244 KW - atmospheric-pressure plasma-induced polymerization KW - functional polymers KW - chemical composition KW - thin films KW - biosensing UR - https://pubs.acs.org/doi/10.1021/acsami.0c01443 L2 - https://pubs.acs.org/doi/10.1021/acsami.0c01443 N2 - The capabilities of biosensors for fast, economic, and user-friendly analysis of complex samples has led to the exploitation of analytical devices for detection, quantification, and monitoring of specific chemical species for various applications. For a sufficiently high surface reactivity toward the adopted bioreceptors, a thin functional layer is required to enable coupling of the target biomolecules and to provide good stability in the presence of a sample matrix. In this work, the generation of water-stable oxygen-rich plasma polymerized (pp) films deposited by atmospheric-pressure jet plasma for reliable immobilization of biomolecules is presented. Three types of pp films were developed and characterized. All of the obtained pp films were successfully used as a matrix layer in the SPR immunosensors, which provided excellent level of sensitivity, stability, and regenerability. The achieved results show that atmospheric pressure plasma-induced polymerization is a powerful alternative method for the preparation of matrix layers for a wide range of applications in the biological field. ER -
MAKHNEVA, Ekaterina, Laura BARILLAS, Zdeněk FARKA, Matěj PASTUCHA, Petr SKLÁDAL, Klaus-Dieter WELTMANN and Katja FRICKE. Functional Plasma Polymerized Surfaces for Biosensing. \textit{ACS Applied Materials \&{} Interfaces}. Washington, DC: American Chemical Society, 2020, vol.~12, No~14, p.~17100-17112. ISSN~1944-8244. Available from: https://dx.doi.org/10.1021/acsami.0c01443.
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