Functional Plasma Polymerized Surfaces for Biosensing

J 2020

Functional Plasma Polymerized Surfaces for Biosensing

MAKHNEVA, Ekaterina, Laura BARILLAS, Zdeněk FARKA, Matěj PASTUCHA, Petr SKLÁDAL et. al.

Basic information

Original name

Functional Plasma Polymerized Surfaces for Biosensing

Authors

MAKHNEVA, Ekaterina (643 Russian Federation), Laura BARILLAS, Zdeněk FARKA (203 Czech Republic, belonging to the institution), Matěj PASTUCHA (203 Czech Republic, belonging to the institution), Petr SKLÁDAL (203 Czech Republic, guarantor, belonging to the institution), Klaus-Dieter WELTMANN and Katja FRICKE

Edition

ACS Applied Materials & Interfaces, Washington, DC, American Chemical Society, 2020, 1944-8244

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10305 Fluids and plasma physics

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 9.229

RIV identification code

RIV/00216224:14740/20:00115502

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1021/acsami.0c01443

UT WoS

000526583500119

Keywords in English

atmospheric-pressure plasma-induced polymerization; functional polymers; chemical composition; thin films; biosensing

Abstract

V originále

The capabilities of biosensors for fast, economic, and user-friendly analysis of complex samples has led to the exploitation of analytical devices for detection, quantification, and monitoring of specific chemical species for various applications. For a sufficiently high surface reactivity toward the adopted bioreceptors, a thin functional layer is required to enable coupling of the target biomolecules and to provide good stability in the presence of a sample matrix. In this work, the generation of water-stable oxygen-rich plasma polymerized (pp) films deposited by atmospheric-pressure jet plasma for reliable immobilization of biomolecules is presented. Three types of pp films were developed and characterized. All of the obtained pp films were successfully used as a matrix layer in the SPR immunosensors, which provided excellent level of sensitivity, stability, and regenerability. The achieved results show that atmospheric pressure plasma-induced polymerization is a powerful alternative method for the preparation of matrix layers for a wide range of applications in the biological field.

Links

LM2018127, research and development project

Name: Česká infrastruktura pro integrativní strukturní biologii (Acronym: CIISB)

Investor: Ministry of Education, Youth and Sports of the CR

LQ1601, research and development project

Name: CEITEC 2020 (Acronym: CEITEC2020)

Investor: Ministry of Education, Youth and Sports of the CR

MUNI/A/1252/2019, interní kód MU

Name: Podpora biochemického výzkumu v roce 2020

Investor: Masaryk University, Category A

Citovat

MAKHNEVA, Ekaterina, Laura BARILLAS, Zdeněk FARKA, Matěj PASTUCHA, Petr SKLÁDAL, Klaus-Dieter WELTMANN and Katja FRICKE. Functional Plasma Polymerized Surfaces for Biosensing. ACS Applied Materials & Interfaces. Washington, DC: American Chemical Society, 2020, vol. 12, No 14, p. 17100-17112. ISSN 1944-8244. Available from: https://dx.doi.org/10.1021/acsami.0c01443.

@article{1644003,
   author = {Makhneva, Ekaterina and Barillas, Laura and Farka, Zdeněk and Pastucha, Matěj and Skládal, Petr and Weltmann, KlausandDieter and Fricke, Katja},
   article_location = {Washington, DC},
   article_number = {14},
   doi = {http://dx.doi.org/10.1021/acsami.0c01443},
   keywords = {atmospheric-pressure plasma-induced polymerization; functional polymers; chemical composition; thin films; biosensing},
   language = {eng},
   issn = {1944-8244},
   journal = {ACS Applied Materials & Interfaces},
   title = {Functional Plasma Polymerized Surfaces for Biosensing},
   url = {https://pubs.acs.org/doi/10.1021/acsami.0c01443},
   volume = {12},
   year = {2020}
}

TY  - JOUR
ID  - 1644003
AU  - Makhneva, Ekaterina - Barillas, Laura - Farka, Zdeněk - Pastucha, Matěj - Skládal, Petr - Weltmann, Klaus-Dieter - Fricke, Katja
PY  - 2020
TI  - Functional Plasma Polymerized Surfaces for Biosensing
JF  - ACS Applied Materials & Interfaces
VL  - 12
IS  - 14
SP  - 17100-17112
EP  - 17100-17112
PB  - American Chemical Society
SN  - 19448244
KW  - atmospheric-pressure plasma-induced polymerization
KW  - functional polymers
KW  - chemical composition
KW  - thin films
KW  - biosensing
UR  - https://pubs.acs.org/doi/10.1021/acsami.0c01443
L2  - https://pubs.acs.org/doi/10.1021/acsami.0c01443
N2  - The capabilities of biosensors for fast, economic, and user-friendly analysis of complex samples has led to the exploitation of analytical devices for detection, quantification, and monitoring of specific chemical species for various applications. For a sufficiently high surface reactivity toward the adopted bioreceptors, a thin functional layer is required to enable coupling of the target biomolecules and to provide good stability in the presence of a sample matrix. In this work, the generation of water-stable oxygen-rich plasma polymerized (pp) films deposited by atmospheric-pressure jet plasma for reliable immobilization of biomolecules is presented. Three types of pp films were developed and characterized. All of the obtained pp films were successfully used as a matrix layer in the SPR immunosensors, which provided excellent level of sensitivity, stability, and regenerability. The achieved results show that atmospheric pressure plasma-induced polymerization is a powerful alternative method for the preparation of matrix layers for a wide range of applications in the biological field.
ER  -

MAKHNEVA, Ekaterina, Laura BARILLAS, Zdeněk FARKA, Matěj PASTUCHA, Petr SKLÁDAL, Klaus-Dieter WELTMANN and Katja FRICKE. Functional Plasma Polymerized Surfaces for Biosensing. \textit{ACS Applied Materials \&{} Interfaces}. Washington, DC: American Chemical Society, 2020, vol.~12, No~14, p.~17100-17112. ISSN~1944-8244. Available from: https://dx.doi.org/10.1021/acsami.0c01443.

Detailed Information on Publication Record