Surface-enhanced Raman spectroscopy of chloroalkanes in
microfluidic chips

D 2018

Surface-enhanced Raman spectroscopy of chloroalkanes in microfluidic chips

PILAT, Z., M. KIZOVSKY, J. JEZEK, S. KRATKY, J. SOBOTA et. al.

Basic information

Original name

Surface-enhanced Raman spectroscopy of chloroalkanes in microfluidic chips

Authors

PILAT, Z. (guarantor), M. KIZOVSKY, J. JEZEK, S. KRATKY, J. SOBOTA, M. SILER, O. SAMEK, Tomáš BURYŠKA (203 Czech Republic, belonging to the institution), Pavel VAŇÁČEK (203 Czech Republic, belonging to the institution), Jiří DAMBORSKÝ (203 Czech Republic, belonging to the institution), Zbyněk PROKOP (203 Czech Republic, belonging to the institution) and Pavel ZEMANEK

Edition

BELLINGHAM, 21ST CZECH-POLISH-SLOVAK OPTICAL CONFERENCE ON WAVE AND QUANTUM ASPECTS OF CONTEMPORARY OPTICS, p. 1-7, 7 pp. 2018

Publisher

SPIE-INT SOC OPTICAL ENGINEERING

Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

10306 Optics

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Publication form

electronic version available online

References:

URL

RIV identification code

RIV/00216224:14310/18:00108257

Organization unit

Faculty of Science

ISBN

978-1-5106-2608-9

ISSN

DOI

http://dx.doi.org/10.1117/12.2518393

UT WoS

000455324600044

Keywords in English

Surface enhanced Raman spectroscopy; microfluidics; Klarite 312; chloroalkane; 1.2.3-trichloropropane

Abstract

V originále

Optofluidics, a research discipline combining optics and microfluidics, currently aspires to revolutionize the analysis of biological and chemical samples, e.g. for medicine, pharmacology, or molecular biology. In order to detect low concentrations of analytes in water, we have developed an optofluidic device containing a nanostructured substrate for surface enhanced Raman spectroscopy (SERS). The geometry of the gold surface allows localized plasmon oscillations to give rise to the SERS effect, in which the Raman spectral lines are intensified by the interaction of the plasmonic field with the electrons in the molecular bonds. The SERS substrate was enclosed in a microfluidic system, which allowed transport and precise mixing of the analyzed fluids, while preventing contamination or abrasion of the highly sensitive substrate. To illustrate its practical use, we employed the device for quantitative detection of persistent environmental pollutant 1,2,3-trichloropropane in water in submillimolar concentrations. The developed sensor allows fast and simple quantification of halogenated compounds and it will contribute towards the environmental monitoring and enzymology experiments with engineered haloalkane dehalogenase enzymes.

Links

GA16-07965S, research and development project

Name: Řízená evoluce dynamických elementů v enzymech s využitím mikrofluidních čipů

Investor: Czech Science Foundation

LM2015051, research and development project

Name: Centrum pro výzkum toxických látek v prostředí (Acronym: RECETOX RI)

Investor: Ministry of Education, Youth and Sports of the CR

LO1214, research and development project

Name: Centrum pro výzkum toxických látek v prostředí (Acronym: RECETOX)

Investor: Ministry of Education, Youth and Sports of the CR

Citovat

PILAT, Z., M. KIZOVSKY, J. JEZEK, S. KRATKY, J. SOBOTA, M. SILER, O. SAMEK, Tomáš BURYŠKA, Pavel VAŇÁČEK, Jiří DAMBORSKÝ, Zbyněk PROKOP and Pavel ZEMANEK. Surface-enhanced Raman spectroscopy of chloroalkanes in microfluidic chips. Online. In Zemanek, P. 21ST CZECH-POLISH-SLOVAK OPTICAL CONFERENCE ON WAVE AND QUANTUM ASPECTS OF CONTEMPORARY OPTICS. BELLINGHAM: SPIE-INT SOC OPTICAL ENGINEERING, 2018, p. 1-7. ISBN 978-1-5106-2608-9. Available from: https://dx.doi.org/10.1117/12.2518393.

@inproceedings{1644839,
   author = {Pilat, Z. and Kizovsky, M. and Jezek, J. and Kratky, S. and Sobota, J. and Siler, M. and Samek, O. and Buryška, Tomáš and Vaňáček, Pavel and Damborský, Jiří and Prokop, Zbyněk and Zemanek, Pavel},
   address = {BELLINGHAM},
   booktitle = {21ST CZECH-POLISH-SLOVAK OPTICAL CONFERENCE ON WAVE AND QUANTUM ASPECTS OF CONTEMPORARY OPTICS},
   doi = {http://dx.doi.org/10.1117/12.2518393},
   editor = {Zemanek, P},
   keywords = {Surface enhanced Raman spectroscopy; microfluidics; Klarite 312; chloroalkane; 1.2.3-trichloropropane},
   howpublished = {elektronická verze "online"},
   language = {eng},
   location = {BELLINGHAM},
   isbn = {978-1-5106-2608-9},
   pages = {1-7},
   publisher = {SPIE-INT SOC OPTICAL ENGINEERING},
   title = {Surface-enhanced Raman spectroscopy of chloroalkanes in microfluidic chips},
   url = {https://www.spiedigitallibrary.org/conference-proceedings-of-spie/10976/1097619/Surface-enhanced-Raman-spectroscopy-of-chloroalkanes-in-microfluidic-chips/10.1117/12.2518393.short?SSO=1},
   year = {2018}
}

TY  - JOUR
ID  - 1644839
AU  - Pilat, Z. - Kizovsky, M. - Jezek, J. - Kratky, S. - Sobota, J. - Siler, M. - Samek, O. - Buryška, Tomáš - Vaňáček, Pavel - Damborský, Jiří - Prokop, Zbyněk - Zemanek, Pavel
PY  - 2018
TI  - Surface-enhanced Raman spectroscopy of chloroalkanes in microfluidic chips
PB  - SPIE-INT SOC OPTICAL ENGINEERING
CY  - BELLINGHAM
SN  - 9781510626089
KW  - Surface enhanced Raman spectroscopy
KW  - microfluidics
KW  - Klarite 312
KW  - chloroalkane
KW  - 1.2.3-trichloropropane
UR  - https://www.spiedigitallibrary.org/conference-proceedings-of-spie/10976/1097619/Surface-enhanced-Raman-spectroscopy-of-chloroalkanes-in-microfluidic-chips/10.1117/12.2518393.short?SSO=1
L2  - https://www.spiedigitallibrary.org/conference-proceedings-of-spie/10976/1097619/Surface-enhanced-Raman-spectroscopy-of-chloroalkanes-in-microfluidic-chips/10.1117/12.2518393.short?SSO=1
N2  - Optofluidics, a research discipline combining optics and microfluidics, currently aspires to revolutionize the analysis of biological and chemical samples, e.g. for medicine, pharmacology, or molecular biology. In order to detect low concentrations of analytes in water, we have developed an optofluidic device containing a nanostructured substrate for surface enhanced Raman spectroscopy (SERS). The geometry of the gold surface allows localized plasmon oscillations to give rise to the SERS effect, in which the Raman spectral lines are intensified by the interaction of the plasmonic field with the electrons in the molecular bonds. The SERS substrate was enclosed in a microfluidic system, which allowed transport and precise mixing of the analyzed fluids, while preventing contamination or abrasion of the highly sensitive substrate. To illustrate its practical use, we employed the device for quantitative detection of persistent environmental pollutant 1,2,3-trichloropropane in water in submillimolar concentrations. The developed sensor allows fast and simple quantification of halogenated compounds and it will contribute towards the environmental monitoring and enzymology experiments with engineered haloalkane dehalogenase enzymes.
ER  -

PILAT, Z., M. KIZOVSKY, J. JEZEK, S. KRATKY, J. SOBOTA, M. SILER, O. SAMEK, Tomáš BURYŠKA, Pavel VAŇÁČEK, Jiří DAMBORSKÝ, Zbyněk PROKOP and Pavel ZEMANEK. Surface-enhanced Raman spectroscopy of chloroalkanes in microfluidic chips. Online. In Zemanek, P. \textit{21ST CZECH-POLISH-SLOVAK OPTICAL CONFERENCE ON WAVE AND QUANTUM ASPECTS OF CONTEMPORARY OPTICS}. BELLINGHAM: SPIE-INT SOC OPTICAL ENGINEERING, 2018, p.~1-7. ISBN~978-1-5106-2608-9. Available from: https://dx.doi.org/10.1117/12.2518393.

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