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@inproceedings{1644839,
author = {Pilat, Z. and Kizovsky, M. and Jezek, J. and Kratky, S. and Sobota, J. and Siler, M. and Samek, O. and Buryška, Tomáš and Vaňáček, Pavel and Damborský, Jiří and Prokop, Zbyněk and Zemanek, Pavel},
address = {BELLINGHAM},
booktitle = {21ST CZECH-POLISH-SLOVAK OPTICAL CONFERENCE ON WAVE AND QUANTUM ASPECTS OF CONTEMPORARY OPTICS},
doi = {http://dx.doi.org/10.1117/12.2518393},
editor = {Zemanek, P},
keywords = {Surface enhanced Raman spectroscopy; microfluidics; Klarite 312; chloroalkane; 1.2.3-trichloropropane},
howpublished = {elektronická verze "online"},
language = {eng},
location = {BELLINGHAM},
isbn = {978-1-5106-2608-9},
pages = {1-7},
publisher = {SPIE-INT SOC OPTICAL ENGINEERING},
title = {Surface-enhanced Raman spectroscopy of chloroalkanes in microfluidic chips},
url = {https://www.spiedigitallibrary.org/conference-proceedings-of-spie/10976/1097619/Surface-enhanced-Raman-spectroscopy-of-chloroalkanes-in-microfluidic-chips/10.1117/12.2518393.short?SSO=1},
year = {2018}
}
TY - JOUR
ID - 1644839
AU - Pilat, Z. - Kizovsky, M. - Jezek, J. - Kratky, S. - Sobota, J. - Siler, M. - Samek, O. - Buryška, Tomáš - Vaňáček, Pavel - Damborský, Jiří - Prokop, Zbyněk - Zemanek, Pavel
PY - 2018
TI - Surface-enhanced Raman spectroscopy of chloroalkanes in microfluidic chips
PB - SPIE-INT SOC OPTICAL ENGINEERING
CY - BELLINGHAM
SN - 9781510626089
KW - Surface enhanced Raman spectroscopy
KW - microfluidics
KW - Klarite 312
KW - chloroalkane
KW - 1.2.3-trichloropropane
UR - https://www.spiedigitallibrary.org/conference-proceedings-of-spie/10976/1097619/Surface-enhanced-Raman-spectroscopy-of-chloroalkanes-in-microfluidic-chips/10.1117/12.2518393.short?SSO=1
L2 - https://www.spiedigitallibrary.org/conference-proceedings-of-spie/10976/1097619/Surface-enhanced-Raman-spectroscopy-of-chloroalkanes-in-microfluidic-chips/10.1117/12.2518393.short?SSO=1
N2 - Optofluidics, a research discipline combining optics and microfluidics, currently aspires to revolutionize the analysis of biological and chemical samples, e.g. for medicine, pharmacology, or molecular biology. In order to detect low concentrations of analytes in water, we have developed an optofluidic device containing a nanostructured substrate for surface enhanced Raman spectroscopy (SERS). The geometry of the gold surface allows localized plasmon oscillations to give rise to the SERS effect, in which the Raman spectral lines are intensified by the interaction of the plasmonic field with the electrons in the molecular bonds. The SERS substrate was enclosed in a microfluidic system, which allowed transport and precise mixing of the analyzed fluids, while preventing contamination or abrasion of the highly sensitive substrate. To illustrate its practical use, we employed the device for quantitative detection of persistent environmental pollutant 1,2,3-trichloropropane in water in submillimolar concentrations. The developed sensor allows fast and simple quantification of halogenated compounds and it will contribute towards the environmental monitoring and enzymology experiments with engineered haloalkane dehalogenase enzymes.
ER -
PILAT, Z., M. KIZOVSKY, J. JEZEK, S. KRATKY, J. SOBOTA, M. SILER, O. SAMEK, Tomáš BURYŠKA, Pavel VAŇÁČEK, Jiří DAMBORSKÝ, Zbyněk PROKOP and Pavel ZEMANEK. Surface-enhanced Raman spectroscopy of chloroalkanes in microfluidic chips. Online. In Zemanek, P. \textit{21ST CZECH-POLISH-SLOVAK OPTICAL CONFERENCE ON WAVE AND QUANTUM ASPECTS OF CONTEMPORARY OPTICS}. BELLINGHAM: SPIE-INT SOC OPTICAL ENGINEERING, 2018, p.~1-7. ISBN~978-1-5106-2608-9. Available from: https://dx.doi.org/10.1117/12.2518393.
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