The role of the striatum in visuomotor integration during
handwriting: an fMRI study

J 2020

The role of the striatum in visuomotor integration during handwriting: an fMRI study

BARTOŇ, Marek, Monika FŇAŠKOVÁ, Irena REKTOROVÁ, Michal MIKL, Radek MAREČEK et. al.

Basic information

Original name

The role of the striatum in visuomotor integration during handwriting: an fMRI study

Authors

BARTOŇ, Marek (203 Czech Republic, belonging to the institution), Monika FŇAŠKOVÁ (203 Czech Republic, belonging to the institution), Irena REKTOROVÁ (203 Czech Republic, belonging to the institution), Michal MIKL (203 Czech Republic, belonging to the institution), Radek MAREČEK (203 Czech Republic, belonging to the institution), S.Z. RAPCSAK and Ivan REKTOR (203 Czech Republic, guarantor, belonging to the institution)

Edition

Journal of Neural Transmission, WIEN, SPRINGER WIEN, 2020, 0300-9564

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30210 Clinical neurology

Country of publisher

Austria

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.575

RIV identification code

RIV/00216224:14740/20:00115518

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1007/s00702-019-02131-8

UT WoS

000505427000001

Keywords in English

Basal ganglia; fMRI; Functional connectivity; Handwriting; Striatum; Visuomotor integration

Abstract

V originále

This study investigates the role of the dorsal/sensorimotor striatum in visuomotor integration (i.e., the transformation of internal visual information about letter shapes into motor output) during handwriting. Twenty healthy participants underwent fMRI scanning with tasks consisting of self-paced handwriting of alphabetically ordered single letters and simple dots, with both tasks performed without visual feedback. Functional connectivity (FC) from these two tasks was compared to demonstrate the difference between coordinated activity arising during handwriting and the activity during a simpler motor condition. Our study focused upon the writing-specific cortico-striatal network of preselected regions of interest consisting of the visual word form area (VWFA), anterior intraparietal sulcus/superior parietal lobule, striatum, premotor cortex/Exner's area, and primary and supplementary motor regions. We observed systematically increased task-induced cortico-striatal and cortico-cortical FC. This increased synchronization of neural activity between the VWFA, i.e., the visual cortical area containing information about letter shapes, and the frontoparietal motor regions is mediated by the striatum. These findings suggest the involvement of the striatum in integrating stored letter-shape information with motor planning and execution during handwriting.

Links

EF16_013/0001775, research and development project

Name: Modernizace a podpora výzkumných aktivit národní infrastruktury pro biologické a medicínské zobrazování Czech-BioImaging

90062, large research infrastructures

Name: Czech-BioImaging

Citovat

BARTOŇ, Marek, Monika FŇAŠKOVÁ, Irena REKTOROVÁ, Michal MIKL, Radek MAREČEK, S.Z. RAPCSAK and Ivan REKTOR. The role of the striatum in visuomotor integration during handwriting: an fMRI study. Journal of Neural Transmission. WIEN: SPRINGER WIEN, 2020, vol. 127, No 3, p. 331-337. ISSN 0300-9564. Available from: https://dx.doi.org/10.1007/s00702-019-02131-8.

@article{1645017,
   author = {Bartoň, Marek and Fňašková, Monika and Rektorová, Irena and Mikl, Michal and Mareček, Radek and Rapcsak, S.Z. and Rektor, Ivan},
   article_location = {WIEN},
   article_number = {3},
   doi = {http://dx.doi.org/10.1007/s00702-019-02131-8},
   keywords = {Basal ganglia; fMRI; Functional connectivity; Handwriting; Striatum; Visuomotor integration},
   language = {eng},
   issn = {0300-9564},
   journal = {Journal of Neural Transmission},
   title = {The role of the striatum in visuomotor integration during handwriting: an fMRI study},
   url = {https://link.springer.com/article/10.1007%2Fs00702-019-02131-8},
   volume = {127},
   year = {2020}
}

TY  - JOUR
ID  - 1645017
AU  - Bartoň, Marek - Fňašková, Monika - Rektorová, Irena - Mikl, Michal - Mareček, Radek - Rapcsak, S.Z. - Rektor, Ivan
PY  - 2020
TI  - The role of the striatum in visuomotor integration during handwriting: an fMRI study
JF  - Journal of Neural Transmission
VL  - 127
IS  - 3
SP  - 331-337
EP  - 331-337
PB  - SPRINGER WIEN
SN  - 03009564
KW  - Basal ganglia
KW  - fMRI
KW  - Functional connectivity
KW  - Handwriting
KW  - Striatum
KW  - Visuomotor integration
UR  - https://link.springer.com/article/10.1007%2Fs00702-019-02131-8
L2  - https://link.springer.com/article/10.1007%2Fs00702-019-02131-8
N2  - This study investigates the role of the dorsal/sensorimotor striatum in visuomotor integration (i.e., the transformation of internal visual information about letter shapes into motor output) during handwriting. Twenty healthy participants underwent fMRI scanning with tasks consisting of self-paced handwriting of alphabetically ordered single letters and simple dots, with both tasks performed without visual feedback. Functional connectivity (FC) from these two tasks was compared to demonstrate the difference between coordinated activity arising during handwriting and the activity during a simpler motor condition. Our study focused upon the writing-specific cortico-striatal network of preselected regions of interest consisting of the visual word form area (VWFA), anterior intraparietal sulcus/superior parietal lobule, striatum, premotor cortex/Exner's area, and primary and supplementary motor regions. We observed systematically increased task-induced cortico-striatal and cortico-cortical FC. This increased synchronization of neural activity between the VWFA, i.e., the visual cortical area containing information about letter shapes, and the frontoparietal motor regions is mediated by the striatum. These findings suggest the involvement of the striatum in integrating stored letter-shape information with motor planning and execution during handwriting.
ER  -

BARTOŇ, Marek, Monika FŇAŠKOVÁ, Irena REKTOROVÁ, Michal MIKL, Radek MAREČEK, S.Z. RAPCSAK and Ivan REKTOR. The role of the striatum in visuomotor integration during handwriting: an fMRI study. \textit{Journal of Neural Transmission}. WIEN: SPRINGER WIEN, 2020, vol.~127, No~3, p.~331-337. ISSN~0300-9564. Available from: https://dx.doi.org/10.1007/s00702-019-02131-8.

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