JANČÁLEK, Radim, Tomáš KAZDA, Renata BELANOVÁ, Petr POSPÍŠIL, Petr BURKOŇ, Ludmila HYNKOVÁ, Pavel ŠLAMPA and Radek LAKOMÝ. RAPID EARLY PROGRESSION OF GLIOBLASTOMA IS NOT RELATED TO CORTICAL/NEURAL STEM CELLS REGIONS. In 14th Meeting of the European-Association-of-Neuro-Oncology (EANO). 2019. ISSN 1522-8517. Available from: https://dx.doi.org/10.1093/neuonc/noz126.342.
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Basic information
Original name RAPID EARLY PROGRESSION OF GLIOBLASTOMA IS NOT RELATED TO CORTICAL/NEURAL STEM CELLS REGIONS
Authors JANČÁLEK, Radim (203 Czech Republic, guarantor, belonging to the institution), Tomáš KAZDA (203 Czech Republic, belonging to the institution), Renata BELANOVÁ (203 Czech Republic), Petr POSPÍŠIL (203 Czech Republic), Petr BURKOŇ (203 Czech Republic), Ludmila HYNKOVÁ (203 Czech Republic), Pavel ŠLAMPA (203 Czech Republic) and Radek LAKOMÝ (203 Czech Republic).
Edition 14th Meeting of the European-Association-of-Neuro-Oncology (EANO), 2019.
Other information
Original language English
Type of outcome Conference abstract
Field of Study 30204 Oncology
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 10.247
RIV identification code RIV/00216224:14110/19:00108628
Organization unit Faculty of Medicine
ISSN 1522-8517
Doi http://dx.doi.org/10.1093/neuonc/noz126.342
UT WoS 000493085900344
Keywords in English glioblastoma
Tags rivok
Tags International impact
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 14/4/2020 10:42.
Abstract
Rapid early progression (REP) of glioblastoma after surgery is quite often observed on pre-radiotherapy MR scan. Clinical and molecular biomarkers indicating increased risk of this REP may be of high clinical need. Subventricular brain zone (SVZ) and hippocampal regions are supposed to harbor astrocyte-like neural stem cells with tumors arising from these transformed SVZ stem cells dreaded to be of higher risk of REP. Lim's et al classification of initial glioblastoma location related to these neural stem cells regions was predictive for invasive and multifocal tumor phenotype. The aim of this retrospective single-institutional study is to evaluate the relations of this Lim classification on REP in unselected cohort of glioblastoma patients.
Links
NV18-03-00469, research and development projectName: Reakce neuronální populace hipokampu na stereotaktickou radioterapii extratemporálních mozkových metastáz: vliv na neurokognitivní funkce a zachování kvality života
Investor: Ministry of Health of the CR
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