RAPID EARLY PROGRESSION OF GLIOBLASTOMA IS NOT RELATED TO
CORTICAL/NEURAL STEM CELLS REGIONS

a 2019

RAPID EARLY PROGRESSION OF GLIOBLASTOMA IS NOT RELATED TO CORTICAL/NEURAL STEM CELLS REGIONS

JANČÁLEK, Radim, Tomáš KAZDA, Renata BELANOVÁ, Petr POSPÍŠIL, Petr BURKOŇ et. al.

Basic information

Original name

RAPID EARLY PROGRESSION OF GLIOBLASTOMA IS NOT RELATED TO CORTICAL/NEURAL STEM CELLS REGIONS

Authors

JANČÁLEK, Radim (203 Czech Republic, guarantor, belonging to the institution), Tomáš KAZDA (203 Czech Republic, belonging to the institution), Renata BELANOVÁ (203 Czech Republic), Petr POSPÍŠIL (203 Czech Republic), Petr BURKOŇ (203 Czech Republic), Ludmila HYNKOVÁ (203 Czech Republic), Pavel ŠLAMPA (203 Czech Republic) and Radek LAKOMÝ (203 Czech Republic)

Edition

14th Meeting of the European-Association-of-Neuro-Oncology (EANO), 2019

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30204 Oncology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 10.247

RIV identification code

RIV/00216224:14110/19:00108628

Organization unit

Faculty of Medicine

ISSN

DOI

http://dx.doi.org/10.1093/neuonc/noz126.342

UT WoS

000493085900344

Keywords in English

glioblastoma

Abstract

V originále

Rapid early progression (REP) of glioblastoma after surgery is quite often observed on pre-radiotherapy MR scan. Clinical and molecular biomarkers indicating increased risk of this REP may be of high clinical need. Subventricular brain zone (SVZ) and hippocampal regions are supposed to harbor astrocyte-like neural stem cells with tumors arising from these transformed SVZ stem cells dreaded to be of higher risk of REP. Lim's et al classification of initial glioblastoma location related to these neural stem cells regions was predictive for invasive and multifocal tumor phenotype. The aim of this retrospective single-institutional study is to evaluate the relations of this Lim classification on REP in unselected cohort of glioblastoma patients.

Links

NV18-03-00469, research and development project

Name: Reakce neuronální populace hipokampu na stereotaktickou radioterapii extratemporálních mozkových metastáz: vliv na neurokognitivní funkce a zachování kvality života

Investor: Ministry of Health of the CR

Citovat

JANČÁLEK, Radim, Tomáš KAZDA, Renata BELANOVÁ, Petr POSPÍŠIL, Petr BURKOŇ, Ludmila HYNKOVÁ, Pavel ŠLAMPA and Radek LAKOMÝ. RAPID EARLY PROGRESSION OF GLIOBLASTOMA IS NOT RELATED TO CORTICAL/NEURAL STEM CELLS REGIONS. In 14th Meeting of the European-Association-of-Neuro-Oncology (EANO). 2019. ISSN 1522-8517. Available from: https://dx.doi.org/10.1093/neuonc/noz126.342.

@proceedings{1645037,
   author = {Jančálek, Radim and Kazda, Tomáš and Belanová, Renata and Pospíšil, Petr and Burkoň, Petr and Hynková, Ludmila and Šlampa, Pavel and Lakomý, Radek},
   booktitle = {14th Meeting of the European-Association-of-Neuro-Oncology (EANO)},
   doi = {http://dx.doi.org/10.1093/neuonc/noz126.342},
   keywords = {glioblastoma},
   language = {eng},
   title = {RAPID EARLY PROGRESSION OF GLIOBLASTOMA IS NOT RELATED TO CORTICAL/NEURAL STEM CELLS REGIONS},
   url = {https://academic.oup.com/neuro-oncology/article-abstract/21/Supplement_3/iii93/5564489?redirectedFrom=fulltext},
   year = {2019}
}

TY  - CONF
ID  - 1645037
AU  - Jančálek, Radim - Kazda, Tomáš - Belanová, Renata - Pospíšil, Petr - Burkoň, Petr - Hynková, Ludmila - Šlampa, Pavel - Lakomý, Radek
PY  - 2019
TI  - RAPID EARLY PROGRESSION OF GLIOBLASTOMA IS NOT RELATED TO CORTICAL/NEURAL STEM CELLS REGIONS
KW  - glioblastoma
UR  - https://academic.oup.com/neuro-oncology/article-abstract/21/Supplement_3/iii93/5564489?redirectedFrom=fulltext
L2  - https://academic.oup.com/neuro-oncology/article-abstract/21/Supplement_3/iii93/5564489?redirectedFrom=fulltext
N2  - Rapid early progression (REP) of glioblastoma after surgery is quite often observed on pre-radiotherapy MR scan. Clinical and molecular biomarkers indicating increased risk of this REP may be of high clinical need. Subventricular brain zone (SVZ) and hippocampal regions are supposed to harbor astrocyte-like neural stem cells with tumors arising from these transformed SVZ stem cells dreaded to be of higher risk of REP. Lim's et al classification of initial glioblastoma location related to these neural stem cells regions was predictive for invasive and multifocal tumor phenotype. The aim of this retrospective single-institutional study is to evaluate the relations of this Lim classification on REP in unselected cohort of glioblastoma patients.
ER  -

JANČÁLEK, Radim, Tomáš KAZDA, Renata BELANOVÁ, Petr POSPÍŠIL, Petr BURKOŇ, Ludmila HYNKOVÁ, Pavel ŠLAMPA and Radek LAKOMÝ. RAPID EARLY PROGRESSION OF GLIOBLASTOMA IS NOT RELATED TO CORTICAL/NEURAL STEM CELLS REGIONS. In \textit{14th Meeting of the European-Association-of-Neuro-Oncology (EANO)}. 2019. ISSN~1522-8517. Available from: https://dx.doi.org/10.1093/neuonc/noz126.342.

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