SELINGEROVA, I., Eva BUDINSKÁ, Barbora ZWINSOVÁ, B. MAZALOVA, B. BENCSIKOVA, D. VALIK and L.Z. DUBSKA. Anti-alpha gal antibodies in the context of blood group and stool and tumour-adjacent microbiome in colorectal cancer patients. In Immuno-Oncology Congress of the European-Society-for-Medical-Oncology (ESMO). 2019. ISSN 0923-7534.
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Basic information
Original name Anti-alpha gal antibodies in the context of blood group and stool and tumour-adjacent microbiome in colorectal cancer patients
Authors SELINGEROVA, I., Eva BUDINSKÁ (703 Slovakia, belonging to the institution), Barbora ZWINSOVÁ (203 Czech Republic, belonging to the institution), B. MAZALOVA, B. BENCSIKOVA, D. VALIK and L.Z. DUBSKA.
Edition Immuno-Oncology Congress of the European-Society-for-Medical-Oncology (ESMO), 2019.
Other information
Original language English
Type of outcome Conference abstract
Field of Study 30204 Oncology
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 18.274
RIV identification code RIV/00216224:14310/19:00113691
Organization unit Faculty of Science
ISSN 0923-7534
UT WoS 000506799900096
Keywords in English blood group
Tags rivok
Changed by Changed by: Mgr. Marie Šípková, DiS., učo 437722. Changed: 20/4/2020 16:35.
Abstract
Gut microbiome plays a role in the development and clinical course of colorectal cancer (CRC). Natural antibodies against galactose-a-1,3-galactose (a-gal) are highly abundant in humans due to regular stimulation from gut bacteria. Similarly, Abs against AB0 blood group antigens are produced as cross-reacting with intestinal bacteria and a-gal epitope has similar structure to blood group B Ag. Blood group antigens may be associated with an expansion families of gut bacteria.
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