a 2019

Risk assessment of EDCs in Europe based on human biomonitoring data

SARIGIANNIS, D., S. KARAKITSIOS, A. GOTTI, V. KUMAR, M. SCHUHMACHER et. al.

Basic information

Original name

Risk assessment of EDCs in Europe based on human biomonitoring data

Authors

SARIGIANNIS, D., S. KARAKITSIOS, A. GOTTI, V. KUMAR, M. SCHUHMACHER, C. BROCHOT, A. CREPET, Martin SCHERINGER (756 Switzerland, belonging to the institution), Elena DOMINGUEZ ROMERO (724 Spain), J. BESSEMS, K. BAKEN, M. HORVAT and J. TRATNIK

Edition

55th Congress of the European-Societies-of-Toxicology (EUROTOX) - Toxicology - Science Providing Solutions, 2019

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30108 Toxicology

Country of publisher

Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 3.569

RIV identification code

RIV/00216224:14310/19:00113702

Organization unit

Faculty of Science

ISSN

UT WoS

000484771800797

Keywords in English

human biomonitoring

Tags

Tags

International impact, Reviewed
Změněno: 20/4/2020 20:55, Mgr. Marie Šípková, DiS.

Abstract

V originále

A major advantage of human biomonitoring (HBM) data is that they provide an integrated overview of the body burden to xenobiotics that an individual is exposed to. However, quantification of exposure based on HBM data poses significant challenges that are worth facing, given the opportunities that HBM provides in terms of informing and effectively supporting risk assessment. Based on the above, the aim of this within the HBM4EU project was to derive EU-wide external exposure estimates starting from HBM data and to derive and risk characterization ratio (RCR) by comparing these estimates with existing regulatory thresholds. For the reconstruction of exposure the INTEGRA computational platform was properly parameterised for the compounds of interest, namely bisphenol-A (BPA), phthalates (DEHP, DiNP and DnBP) and DINCH, emerging flame retardants (TCEP) and Perfluorinated compounds (PFOA and PFOS).