Bioactive TiCaPCON-coated PCL nanofibers as a promising
material for bone tissue engineering

J 2019

Bioactive TiCaPCON-coated PCL nanofibers as a promising material for bone tissue engineering

MANAKHOV, A., E.S. PERMYAKOVA, S. ERSHOV, A. SHEVEYKO, A. KOVALSKII et. al.

Basic information

Original name

Bioactive TiCaPCON-coated PCL nanofibers as a promising material for bone tissue engineering

Authors

MANAKHOV, A. (643 Russian Federation), E.S. PERMYAKOVA (643 Russian Federation), S. ERSHOV (643 Russian Federation), A. SHEVEYKO (643 Russian Federation), A. KOVALSKII (643 Russian Federation), J. POLCAK (203 Czech Republic), I.Y. ZHITNYAK (643 Russian Federation), N.A. GLOUSHANKOVA (643 Russian Federation), Lenka ZAJÍČKOVÁ (203 Czech Republic, belonging to the institution) and D.V. SHTANSKY (643 Russian Federation)

Edition

Applied Surface Science, AMSTERDAM, Elsevier Science BV, 2019, 0169-4332

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10400 1.4 Chemical sciences

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 6.182

RIV identification code

RIV/00216224:14740/19:00113735

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1016/j.apsusc.2019.02.163

UT WoS

000464931800097

Keywords in English

PCL; TiCaPCON; Nanofibers; Magnetron sputtering; XPS; Osteoblast

Změněno: 23/4/2020 12:08, Mgr. Michal Petr

Abstract

V originále

This work deals with the deposition of bioactive TiCaPCON films onto biodegradable polycaprolactone (PCL) nanofibers using magnetron sputtering for bone tissue engineering. Low melting point of PCL nanofibers requires a careful tuning of processing parameters in order to achieve high film quality and avoid substrate degradation. SEM and XPS analyses showed that, with the magnetron current of 2 A, the TiCaPCON films deposited onto PCL nanofibers and Si wafers exhibit similar chemical states hereby indicating that the nanofiber structure is not affected by the deposition process. In vitro biological tests indicated that the osteoblasts adhesion and proliferation as well the ALP activity can be significantly improved by depositing the TiCaPCON film onto PCL. The reported findings suggest a new strategy for the preparation of biodegradable polymer-based biomaterials for bone tissue engineering.

Citovat

MANAKHOV, A., E.S. PERMYAKOVA, S. ERSHOV, A. SHEVEYKO, A. KOVALSKII, J. POLCAK, I.Y. ZHITNYAK, N.A. GLOUSHANKOVA, Lenka ZAJÍČKOVÁ and D.V. SHTANSKY. Bioactive TiCaPCON-coated PCL nanofibers as a promising material for bone tissue engineering. Applied Surface Science. AMSTERDAM: Elsevier Science BV, 2019, vol. 479, neuveden, p. 796-802. ISSN 0169-4332. Available from: https://dx.doi.org/10.1016/j.apsusc.2019.02.163.

@article{1648699,
   author = {Manakhov, A. and Permyakova, E.S. and Ershov, S. and Sheveyko, A. and Kovalskii, A. and Polcak, J. and Zhitnyak, I.Y. and Gloushankova, N.A. and Zajíčková, Lenka and Shtansky, D.V.},
   article_location = {AMSTERDAM},
   article_number = {neuveden},
   doi = {http://dx.doi.org/10.1016/j.apsusc.2019.02.163},
   keywords = {PCL; TiCaPCON; Nanofibers; Magnetron sputtering; XPS; Osteoblast},
   language = {eng},
   issn = {0169-4332},
   journal = {Applied Surface Science},
   title = {Bioactive TiCaPCON-coated PCL nanofibers as a promising material for bone tissue engineering},
   url = {https://www.sciencedirect.com/science/article/pii/S0169433219305057?via%3Dihub},
   volume = {479},
   year = {2019}
}

TY  - JOUR
ID  - 1648699
AU  - Manakhov, A. - Permyakova, E.S. - Ershov, S. - Sheveyko, A. - Kovalskii, A. - Polcak, J. - Zhitnyak, I.Y. - Gloushankova, N.A. - Zajíčková, Lenka - Shtansky, D.V.
PY  - 2019
TI  - Bioactive TiCaPCON-coated PCL nanofibers as a promising material for bone tissue engineering
JF  - Applied Surface Science
VL  - 479
IS  - neuveden
SP  - 796-802
EP  - 796-802
PB  - Elsevier Science BV
SN  - 01694332
KW  - PCL
KW  - TiCaPCON
KW  - Nanofibers
KW  - Magnetron sputtering
KW  - XPS
KW  - Osteoblast
UR  - https://www.sciencedirect.com/science/article/pii/S0169433219305057?via%3Dihub
L2  - https://www.sciencedirect.com/science/article/pii/S0169433219305057?via%3Dihub
N2  - This work deals with the deposition of bioactive TiCaPCON films onto biodegradable polycaprolactone (PCL) nanofibers using magnetron sputtering for bone tissue engineering. Low melting point of PCL nanofibers requires a careful tuning of processing parameters in order to achieve high film quality and avoid substrate degradation. SEM and XPS analyses showed that, with the magnetron current of 2 A, the TiCaPCON films deposited onto PCL nanofibers and Si wafers exhibit similar chemical states hereby indicating that the nanofiber structure is not affected by the deposition process. In vitro biological tests indicated that the osteoblasts adhesion and proliferation as well the ALP activity can be significantly improved by depositing the TiCaPCON film onto PCL. The reported findings suggest a new strategy for the preparation of biodegradable polymer-based biomaterials for bone tissue engineering.
ER  -

MANAKHOV, A., E.S. PERMYAKOVA, S. ERSHOV, A. SHEVEYKO, A. KOVALSKII, J. POLCAK, I.Y. ZHITNYAK, N.A. GLOUSHANKOVA, Lenka ZAJÍČKOVÁ and D.V. SHTANSKY. Bioactive TiCaPCON-coated PCL nanofibers as a promising material for bone tissue engineering. \textit{Applied Surface Science}. AMSTERDAM: Elsevier Science BV, 2019, vol.~479, neuveden, p.~796-802. ISSN~0169-4332. Available from: https://dx.doi.org/10.1016/j.apsusc.2019.02.163.

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