Detailed Information on Publication Record
2020
Regional Incidence of Inflammatory Bowel Disease in a Czech Pediatric Population: 16 Years of Experience (2002–2017)
JABANDŽIEV, Petr, Tereza PINKASOVÁ, Lumír KUNOVSKÝ, Jan PAPEŽ, Martin JOUZA et. al.Basic information
Original name
Regional Incidence of Inflammatory Bowel Disease in a Czech Pediatric Population: 16 Years of Experience (2002–2017)
Authors
JABANDŽIEV, Petr (203 Czech Republic, guarantor, belonging to the institution), Tereza PINKASOVÁ (203 Czech Republic, belonging to the institution), Lumír KUNOVSKÝ (203 Czech Republic, belonging to the institution), Jan PAPEŽ (203 Czech Republic, belonging to the institution), Martin JOUZA (203 Czech Republic), Bára KARLÍNOVÁ (203 Czech Republic), Martina NOVÁČKOVÁ (203 Czech Republic), Milan URÍK (703 Slovakia, belonging to the institution), Štefánia AULICKÁ (703 Slovakia, belonging to the institution), Ondřej SLABÝ (203 Czech Republic, belonging to the institution), Júlia BOHOŠOVÁ (703 Slovakia, belonging to the institution), Kateřina BAJEROVÁ (203 Czech Republic), Milan BAJER (203 Czech Republic) and Ajay GOEL (840 United States of America)
Edition
Journal of Pediatric Gastroenterology and Nutrition, Philadelphia, LIPPINCOTT WILLIAMS & WILKINS, 2020, 0277-2116
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30209 Paediatrics
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 2.839
RIV identification code
RIV/00216224:14110/20:00118600
Organization unit
Faculty of Medicine
UT WoS
000561373900015
Keywords in English
children; Crohn disease; Czech Republic; incidence; inflammatory bowel disease; ulcerative colitis
Tags
International impact, Reviewed
Změněno: 26/2/2021 12:15, Mgr. Tereza Miškechová
Abstract
V originále
Objectives: Inflammatory bowel disease (IBD) is today a global disease, the incidence of which is growing in the pediatric population. This prospective study aims to decipher IBD incidence and its trend in a pediatric population through 16 years in the South Moravian Region of the Czech Republic. Methods: We evaluated data concerning 358 pediatric patients with newly diagnosed IBD at University Hospital Brno, which is a gastroenterology center for the entire pediatric population (0-18 years) and cares for all pediatric IBD patients in the South Moravian Region (1,187,667 inhabitants). Results: The study encompassed 3,488,907 children during 16 years. We diagnosed 192 children (53.6%) with Crohn disease (CD), 123 (34.4%) with ulcerative colitis (UC), and 43 (12.0%) with IBD-unclassified (IBD-U). The incidence of IBD increased from 3.8 (CD 2.9, UC 0.9, and IBD-U 0.0) per 100 000/year in 2002 to 14.7 (CD 9.8, UC 4.0, and IBD-U 0.9) per 100,000/year in 2017 (P < 0.001). The overall IBD incidence per 100,000/year was 9.8 (95% confidence interval [CI]: 8.8--10.9). Constituent incidences per 100,000/year were CD 5.2 (95% CI: 4.5--6.0), UC 3.4 (95% CI: 2.8--4.0), and IBD-U 1.2 (95% CI: 0.9--1.6). IBD incidence was projected to reach 18.9 per 100,000/year in 2022. Conclusions: The overall incidence of pediatric IBD in the Czech Republic is increasing, and especially that of CD, whereas trends in UC and IBD-U appear to be constant. These data highlight the need to identify risk factors involved in the rising incidence of IBD.
Links
| NV17-29389A, research and development project |
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