a 2020

Endoscopic recurrence after ileocaecal resection for Crohn's disease relating to microscopic inflammation at resection margins

KUNOVSKÝ, Lumír, Karolina POREDSKÁ, Filip MAREK, Zdeněk KALA, Vladimír PROCHÁZKA et. al.

Basic information

Original name

Endoscopic recurrence after ileocaecal resection for Crohn's disease relating to microscopic inflammation at resection margins

Authors

Edition

ESGE Days 2020, 2020

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30219 Gastroenterology and hepatology

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Organization unit

Faculty of Medicine

DOI

Keywords in English

Crohn's disease; ileocaecal resection; resection margins
Změněno: 8/4/2021 08:42, Mgr. Tereza Miškechová

Abstract

V originále

Aims An early postoperative endoscopic recurrence of Crohn´s disease after ileocaecal resection remains unclear concerning its pathogenesis and risk factors. In our study, we evaluated the influence of histological inflammation at the resection margins on endoscopic recurrence. Methods Patients with CD who underwent ileocaecal resection have been prospectively followed up in our study. The specimens were histologically analysed for inflammation at both of the resection margins (ileal and colonic). We evaluated whether histological results of the resection margins are correlated with endoscopic recurrence of CD based on colonoscopy 6 months after ileocaecal resection. Results We have included 107 patients in our study. Six months after ileocaecal resection, 23 patients (21.5 %) had an endoscopic recurrence of CD. The histological signs of CD at the resection margins were associated with a higher endoscopic recurrence (56.5 % versus 4.8 %, p < 0.001). Conclusions Microscopic inflammation at the resection margins was significantly associated with a higher risk of early postoperative endoscopic recurrence after an ileocaecal resection for CD.