| MODRÁ, Helena, Miroslava PALÍKOVÁ, Pavel HYRŠL, Jana BARTOŇKOVÁ, Ivana PAPEŽÍKOVÁ, Zdenka SVOBODOVÁ, Jana BLAHOVÁ a Jan MAREŠ. Effects of trichothecene mycotoxin T-2 toxin on haematological and immunological parameters of rainbow trout (Oncorhynchus mykiss). Mycotoxin Research. Heidelberg: Springer, 2020, roč. 36, č. 3, s. 319-326. ISSN 0178-7888. Dostupné z: https://dx.doi.org/10.1007/s12550-020-00396-7. |
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@article{1659657,
author = {Modrá, Helena and Palíková, Miroslava and Hyršl, Pavel and Bartoňková, Jana and Papežíková, Ivana and Svobodová, Zdenka and Blahová, Jana and Mareš, Jan},
article_location = {Heidelberg},
article_number = {3},
doi = {http://dx.doi.org/10.1007/s12550-020-00396-7},
keywords = {Fusarium; Fungi; Immunoglobulins; Erythropoiesis; Deoxynivalenol},
language = {eng},
issn = {0178-7888},
journal = {Mycotoxin Research},
title = {Effects of trichothecene mycotoxin T-2 toxin on haematological and immunological parameters of rainbow trout (Oncorhynchus mykiss)},
url = {https://doi.org/10.1007/s12550-020-00396-7},
volume = {36},
year = {2020}
}
TY - JOUR
ID - 1659657
AU - Modrá, Helena - Palíková, Miroslava - Hyršl, Pavel - Bartoňková, Jana - Papežíková, Ivana - Svobodová, Zdenka - Blahová, Jana - Mareš, Jan
PY - 2020
TI - Effects of trichothecene mycotoxin T-2 toxin on haematological and immunological parameters of rainbow trout (Oncorhynchus mykiss)
JF - Mycotoxin Research
VL - 36
IS - 3
SP - 319-326
EP - 319-326
PB - Springer
SN - 01787888
KW - Fusarium
KW - Fungi
KW - Immunoglobulins
KW - Erythropoiesis
KW - Deoxynivalenol
UR - https://doi.org/10.1007/s12550-020-00396-7
L2 - https://doi.org/10.1007/s12550-020-00396-7
N2 - The aim of this study was to assess the effects of T-2 toxin–contaminated feed (at concentrations of 1.0 and 1.8 mg/kg) on the rainbow trout immune system by studying non-specific cellular and humoral immune responses and its effect on red and white blood cells. Consumption of T-2 toxin at both concentrations resulted in significantly increased erythrocyte counts and a decrease in mean corpuscular volume.While a significant decrease in mean corpuscular haemoglobin was observed at both experimental concentrations, the decrease in plasma haemoglobin was only significant at the higher T-2 toxin concentration. Higher T-2 toxin concentrations resulted in a significant increase in leukocyte and lymphocyte count, while absolute phagocyte count and counts of less mature neutrophil granulocyte forms remained unchanged at both concentrations. Non-specific humoral immunity (bactericidal activity measured as complement activation) decreased significantly in both experimental groups when compared with the control. The results of this study show that T-2 toxin in feed at a concentration range of 1.0–1.8 mg/kg influences the immunological defence mechanisms of rainbow trout.
ER -
MODRÁ, Helena, Miroslava PALÍKOVÁ, Pavel HYRŠL, Jana BARTOŇKOVÁ, Ivana PAPEŽÍKOVÁ, Zdenka SVOBODOVÁ, Jana BLAHOVÁ a Jan MAREŠ. Effects of trichothecene mycotoxin T-2 toxin on haematological and immunological parameters of rainbow trout (Oncorhynchus mykiss). \textit{Mycotoxin Research}. Heidelberg: Springer, 2020, roč.~36, č.~3, s.~319-326. ISSN~0178-7888. Dostupné z: https://dx.doi.org/10.1007/s12550-020-00396-7.
|
