Effects of trichothecene mycotoxin T-2 toxin on haematological
and immunological parameters of rainbow trout (Oncorhynchus
mykiss)

J 2020

Effects of trichothecene mycotoxin T-2 toxin on haematological and immunological parameters of rainbow trout (Oncorhynchus mykiss)

MODRÁ, Helena, Miroslava PALÍKOVÁ, Pavel HYRŠL, Jana BARTOŇKOVÁ, Ivana PAPEŽÍKOVÁ et. al.

Basic information

Original name

Effects of trichothecene mycotoxin T-2 toxin on haematological and immunological parameters of rainbow trout (Oncorhynchus mykiss)

Authors

MODRÁ, Helena (203 Czech Republic, guarantor), Miroslava PALÍKOVÁ (203 Czech Republic), Pavel HYRŠL (203 Czech Republic, belonging to the institution), Jana BARTOŇKOVÁ (203 Czech Republic, belonging to the institution), Ivana PAPEŽÍKOVÁ (203 Czech Republic), Zdenka SVOBODOVÁ (203 Czech Republic), Jana BLAHOVÁ (203 Czech Republic) and Jan MAREŠ (203 Czech Republic)

Edition

Mycotoxin Research, Heidelberg, Springer, 2020, 0178-7888

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10617 Marine biology, freshwater biology, limnology

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.833

RIV identification code

RIV/00216224:14310/20:00115719

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.1007/s12550-020-00396-7

UT WoS

000535411500001

Keywords in English

Fusarium; Fungi; Immunoglobulins; Erythropoiesis; Deoxynivalenol

Abstract

V originále

The aim of this study was to assess the effects of T-2 toxin–contaminated feed (at concentrations of 1.0 and 1.8 mg/kg) on the rainbow trout immune system by studying non-specific cellular and humoral immune responses and its effect on red and white blood cells. Consumption of T-2 toxin at both concentrations resulted in significantly increased erythrocyte counts and a decrease in mean corpuscular volume.While a significant decrease in mean corpuscular haemoglobin was observed at both experimental concentrations, the decrease in plasma haemoglobin was only significant at the higher T-2 toxin concentration. Higher T-2 toxin concentrations resulted in a significant increase in leukocyte and lymphocyte count, while absolute phagocyte count and counts of less mature neutrophil granulocyte forms remained unchanged at both concentrations. Non-specific humoral immunity (bactericidal activity measured as complement activation) decreased significantly in both experimental groups when compared with the control. The results of this study show that T-2 toxin in feed at a concentration range of 1.0–1.8 mg/kg influences the immunological defence mechanisms of rainbow trout.

Citovat

MODRÁ, Helena, Miroslava PALÍKOVÁ, Pavel HYRŠL, Jana BARTOŇKOVÁ, Ivana PAPEŽÍKOVÁ, Zdenka SVOBODOVÁ, Jana BLAHOVÁ and Jan MAREŠ. Effects of trichothecene mycotoxin T-2 toxin on haematological and immunological parameters of rainbow trout (Oncorhynchus mykiss). Mycotoxin Research. Heidelberg: Springer, 2020, vol. 36, No 3, p. 319-326. ISSN 0178-7888. Available from: https://dx.doi.org/10.1007/s12550-020-00396-7.

@article{1659657,
   author = {Modrá, Helena and Palíková, Miroslava and Hyršl, Pavel and Bartoňková, Jana and Papežíková, Ivana and Svobodová, Zdenka and Blahová, Jana and Mareš, Jan},
   article_location = {Heidelberg},
   article_number = {3},
   doi = {http://dx.doi.org/10.1007/s12550-020-00396-7},
   keywords = {Fusarium; Fungi; Immunoglobulins; Erythropoiesis; Deoxynivalenol},
   language = {eng},
   issn = {0178-7888},
   journal = {Mycotoxin Research},
   title = {Effects of trichothecene mycotoxin T-2 toxin on haematological and immunological parameters of rainbow trout (Oncorhynchus mykiss)},
   url = {https://doi.org/10.1007/s12550-020-00396-7},
   volume = {36},
   year = {2020}
}

TY  - JOUR
ID  - 1659657
AU  - Modrá, Helena - Palíková, Miroslava - Hyršl, Pavel - Bartoňková, Jana - Papežíková, Ivana - Svobodová, Zdenka - Blahová, Jana - Mareš, Jan
PY  - 2020
TI  - Effects of trichothecene mycotoxin T-2 toxin on haematological and immunological parameters of rainbow trout (Oncorhynchus mykiss)
JF  - Mycotoxin Research
VL  - 36
IS  - 3
SP  - 319-326
EP  - 319-326
PB  - Springer
SN  - 01787888
KW  - Fusarium
KW  - Fungi
KW  - Immunoglobulins
KW  - Erythropoiesis
KW  - Deoxynivalenol
UR  - https://doi.org/10.1007/s12550-020-00396-7
L2  - https://doi.org/10.1007/s12550-020-00396-7
N2  - The aim of this study was to assess the effects of T-2 toxin–contaminated feed (at concentrations of 1.0 and 1.8 mg/kg) on the rainbow trout immune system by studying non-specific cellular and humoral immune responses and its effect on red and white blood cells. Consumption of T-2 toxin at both concentrations resulted in significantly increased erythrocyte counts and a decrease in mean corpuscular volume.While a significant decrease in mean corpuscular haemoglobin was observed at both experimental concentrations, the decrease in plasma haemoglobin was only significant at the higher T-2 toxin concentration. Higher T-2 toxin concentrations resulted in a significant increase in leukocyte and lymphocyte count, while absolute phagocyte count and counts of less mature neutrophil granulocyte forms remained unchanged at both concentrations. Non-specific humoral immunity (bactericidal activity measured as complement activation) decreased significantly in both experimental groups when compared with the control. The results of this study show that T-2 toxin in feed at a concentration range of 1.0–1.8 mg/kg influences the immunological defence mechanisms of rainbow trout.
ER  -

MODRÁ, Helena, Miroslava PALÍKOVÁ, Pavel HYRŠL, Jana BARTOŇKOVÁ, Ivana PAPEŽÍKOVÁ, Zdenka SVOBODOVÁ, Jana BLAHOVÁ and Jan MAREŠ. Effects of trichothecene mycotoxin T-2 toxin on haematological and immunological parameters of rainbow trout (Oncorhynchus mykiss). \textit{Mycotoxin Research}. Heidelberg: Springer, 2020, vol.~36, No~3, p.~319-326. ISSN~0178-7888. Available from: https://dx.doi.org/10.1007/s12550-020-00396-7.

Detailed Information on Publication Record