Spontaneous adenocarcinoma of the gas gland in Nothobranchius
fishes

J 2020

Spontaneous adenocarcinoma of the gas gland in Nothobranchius fishes

DYKOVÁ, Iva, Radim BLAŽEK, Kamila SOUČKOVÁ, Martin REICHARD, Ondřej SLABÝ et. al.

Basic information

Original name

Spontaneous adenocarcinoma of the gas gland in Nothobranchius fishes

Authors

DYKOVÁ, Iva (203 Czech Republic, guarantor, belonging to the institution), Radim BLAŽEK, Kamila SOUČKOVÁ (203 Czech Republic, belonging to the institution), Martin REICHARD and Ondřej SLABÝ (203 Czech Republic, belonging to the institution)

Edition

Diseases of Aquatic Organisms, Oldendorf (Luhe), Inter-Research, 2020, 0177-5103

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10700 1.7 Other natural sciences

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 1.802

RIV identification code

RIV/00216224:14740/20:00114193

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.3354/dao03437

UT WoS

000521736600005

Keywords in English

Nothobranchius fishes; Spontaneous neoplasia; Gas gland adenocarcinoma

Abstract

V originále

Nothobranchius fishes (Cyprinodontiformes), known for their genetically encoded extremely compressed lifespan, are considered an excellent vertebrate model for the research of aging. Unlike the rapid accumulation of data concerning their biology, ecology and genome, knowledge of their age-related diseases, including tumours, is still very limited. This Note reports spontaneous neoplastic lesions in the swim bladder gas glands of Nothobranchius furzeri, N. kadleci and N. orthonotus. Based on light and transmission electron microscopy, the neoplastic proliferation of gas gland cells was classified as adenocarcinoma. There was a concurrent proliferation of haemopoietic cells in the kidney interstitium in all individuals diagnosed with this type of primary neoplasia.

Links

GA19-20873S, research and development project

Name: Klíčové mutace v nádorovém genomu Nothobranchius furzeri: od nádorové biologie k návrhu experimentálního modelu sporadické kancerogeneze

Investor: Czech Science Foundation, Driver mutations in cancer genome of Nothobranchius furzeri: from tumor biology to concept of experimental model of spontaneous carcinogenesis

Citovat

DYKOVÁ, Iva, Radim BLAŽEK, Kamila SOUČKOVÁ, Martin REICHARD and Ondřej SLABÝ. Spontaneous adenocarcinoma of the gas gland in Nothobranchius fishes. Diseases of Aquatic Organisms. Oldendorf (Luhe): Inter-Research, 2020, vol. 137, No 3, p. 205-210. ISSN 0177-5103. Available from: https://dx.doi.org/10.3354/dao03437.

@article{1663960,
   author = {Dyková, Iva and Blažek, Radim and Součková, Kamila and Reichard, Martin and Slabý, Ondřej},
   article_location = {Oldendorf (Luhe)},
   article_number = {3},
   doi = {http://dx.doi.org/10.3354/dao03437},
   keywords = {Nothobranchius fishes; Spontaneous neoplasia; Gas gland adenocarcinoma},
   language = {eng},
   issn = {0177-5103},
   journal = {Diseases of Aquatic Organisms},
   title = {Spontaneous adenocarcinoma of the gas gland in Nothobranchius fishes},
   url = {https://www.int-res.com/abstracts/dao/v137/n3/p205-210/},
   volume = {137},
   year = {2020}
}

TY  - JOUR
ID  - 1663960
AU  - Dyková, Iva - Blažek, Radim - Součková, Kamila - Reichard, Martin - Slabý, Ondřej
PY  - 2020
TI  - Spontaneous adenocarcinoma of the gas gland in Nothobranchius fishes
JF  - Diseases of Aquatic Organisms
VL  - 137
IS  - 3
SP  - 205-210
EP  - 205-210
PB  - Inter-Research
SN  - 01775103
KW  - Nothobranchius fishes
KW  - Spontaneous neoplasia
KW  - Gas gland adenocarcinoma
UR  - https://www.int-res.com/abstracts/dao/v137/n3/p205-210/
L2  - https://www.int-res.com/abstracts/dao/v137/n3/p205-210/
N2  - Nothobranchius fishes (Cyprinodontiformes), known for their genetically encoded extremely compressed lifespan, are considered an excellent vertebrate model for the research of aging. Unlike the rapid accumulation of data concerning their biology, ecology and genome, knowledge of their age-related diseases, including tumours, is still very limited. This Note reports spontaneous neoplastic lesions in the swim bladder gas glands of Nothobranchius furzeri, N. kadleci and N. orthonotus. Based on light and transmission electron microscopy, the neoplastic proliferation of gas gland cells was classified as adenocarcinoma. There was a concurrent proliferation of haemopoietic cells in the kidney interstitium in all individuals diagnosed with this type of primary neoplasia.
ER  -

DYKOVÁ, Iva, Radim BLAŽEK, Kamila SOUČKOVÁ, Martin REICHARD and Ondřej SLABÝ. Spontaneous adenocarcinoma of the gas gland in Nothobranchius fishes. \textit{Diseases of Aquatic Organisms}. Oldendorf (Luhe): Inter-Research, 2020, vol.~137, No~3, p.~205-210. ISSN~0177-5103. Available from: https://dx.doi.org/10.3354/dao03437.

Detailed Information on Publication Record