Electrophysiological cellular effects of sex hormones

BÉBAROVÁ, Markéta. Electrophysiological cellular effects of sex hormones. In Marek Malik. Sex and Cardiac Electrophysiology: Differences in Cardiac Electrical Disorders Between Men and Women. 1st edition. Neuveden: Academic Press, 2020, p. 201-210. ISBN 978-0-12-817728-0. Available from: https://dx.doi.org/10.1016/B978-0-12-817728-0.00017-6.

Basic information

• Original name: Electrophysiological cellular effects of sex hormones
• Authors: BÉBAROVÁ, Markéta (203 Czech Republic, guarantor, belonging to the institution).
• Edition: 1st edition. Neuveden, Sex and Cardiac Electrophysiology: Differences in Cardiac Electrical Disorders Between Men and Women, p. 201-210, 10 pp. 2020.
• Publisher: Academic Press

Other information

• Original language: English
• Type of outcome: Chapter(s) of a specialized book
• Field of Study: 30105 Physiology
• Country of publisher: United Kingdom of Great Britain and Northern Ireland
• Confidentiality degree: is not subject to a state or trade secret
• Publication form: printed version "print"
• WWW: URL
• RIV identification code: RIV/00216224:14110/20:00115953
• Organization unit: Faculty of Medicine
• ISBN: 978-0-12-817728-0
• Doi: http://dx.doi.org/10.1016/B978-0-12-817728-0.00017-6
• Keywords in English: sex hormones; testosterone; progesterone; estrogen; ionic channel; ionic current; action potential
• Tags: rivok, topvydavatel
• Tags: International impact, Reviewed

Abstract

Women are known to be more susceptible to long-QT syndrome and related arrhythmias, namely torsades de pointes [1], also in relation to use of various drugs, both cardiac and noncardiac (for a review see Ref. [2]). On the other hand, the incidence of Brugada syndrome and related arrhythmias is higher in men [3]. Sex differences in the susceptibility to arrhythmias were also demonstrated in experiments on various animal species, including rabbit [4] or dog [5]. Some of the sex-specific features of cardiac electrophysiology underlying the varying susceptibility of men and women to various types of arrhythmias have been already revealed, as will be discussed in this chapter. Gaps in the knowledge will be identified.

Links

• MUNI/A/1307/2019, interní kód MU: Name: Kardiovaskulární systém od A do Z (Acronym: KAVASAZ)

Investor: Masaryk University, Category A