Fertility-Related Wishes and Concerns of Adolescent Cancer
Patients and Their Parents

J 2020

Fertility-Related Wishes and Concerns of Adolescent Cancer Patients and Their Parents

KORTE, E., R. SCHILLING, M. BALCEREK, J. BYRNE, U. DIRKSEN et. al.

Basic information

Original name

Fertility-Related Wishes and Concerns of Adolescent Cancer Patients and Their Parents

Authors

KORTE, E. (276 Germany), R. SCHILLING (276 Germany), M. BALCEREK (276 Germany), J. BYRNE (372 Ireland), U. DIRKSEN (276 Germany), G. HERRMANN (276 Germany), Tomáš KEPÁK (203 Czech Republic, belonging to the institution), S. KLCO-BROSIUS (276 Germany), J. KRUSEOVA (203 Czech Republic), M. KUNSTREICH (276 Germany), T. LANGER (276 Germany), A. PANASIUK (616 Poland), J. STEFANOWICZ (616 Poland), G. STRAUSS (276 Germany), K. WIEGELE (40 Austria) and A. BORGMANN-STAUDT (276 Germany)

Edition

JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY, NEW ROCHELLE, MARY ANN LIEBERT, INC, 2020, 2156-5333

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30204 Oncology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 2.223

RIV identification code

RIV/00216224:14110/20:00115969

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1089/jayao.2019.0064

UT WoS

000490990400001

Keywords in English

fertility impairment; fertility preservation; cryopreservation; shared decision-making; fertility-related wishes and concerns; patient education

Abstract

V originále

Purpose: Within a multicenter European study, we explored fertility-related wishes, concerns, and decision-making of adolescent cancer patients and their parents. Patients and Methods: Patients and parents were each asked to complete a fertility-related questionnaire 3 months after initial diagnosis. In total, 113 of 142 (79.6%) eligible patients participated; 53.1% were male and the median age was 16 years (range 13-20 years). The questionnaire was completed by 111 parents. Univariate analyses were conducted using nonparametric methods with alpha = 5%. For multivariate analyses, binary logistic regression was conducted. Results: Both patients (86.1%) and parents (96.3%) indicated a strong desire for biological parenthood for themselves/their children. Female patients (odds ratio [OR] = 3.70; confidence interval [CI]: 1.43-9.50) and parents (OR = 2.70; CI: 1.21-6.00) were more likely to report a high fear of cancer recurrence. Patients who estimated their risk for fertility impairment being high were more likely to be concerned about their fertility (OR = 5.69; CI: 1.41-22.98). Parents who received fertility preservation information were more likely to recommend its use to their children (OR = 5.50; CI: 1.07-28.40), whereas parents of female patients were less likely to do so (OR = 0.13; CI: 0.03-0.61). Conclusions: The prospect of fertility following cancer treatment is important for adolescent cancer patients and their parents, yet it is associated with many concerns. Counseling regarding fertility preservation can be more effective when the individual needs of patients and their parents are taken into consideration.

Citovat

KORTE, E., R. SCHILLING, M. BALCEREK, J. BYRNE, U. DIRKSEN, G. HERRMANN, Tomáš KEPÁK, S. KLCO-BROSIUS, J. KRUSEOVA, M. KUNSTREICH, T. LANGER, A. PANASIUK, J. STEFANOWICZ, G. STRAUSS, K. WIEGELE and A. BORGMANN-STAUDT. Fertility-Related Wishes and Concerns of Adolescent Cancer Patients and Their Parents. JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY. NEW ROCHELLE: MARY ANN LIEBERT, INC, 2020, vol. 9, No 1, p. 55-62. ISSN 2156-5333. Available from: https://dx.doi.org/10.1089/jayao.2019.0064.

@article{1670217,
   author = {Korte, E. and Schilling, R. and Balcerek, M. and Byrne, J. and Dirksen, U. and Herrmann, G. and Kepák, Tomáš and KlcoandBrosius, S. and Kruseova, J. and Kunstreich, M. and Langer, T. and Panasiuk, A. and Stefanowicz, J. and Strauss, G. and Wiegele, K. and BorgmannandStaudt, A.},
   article_location = {NEW ROCHELLE},
   article_number = {1},
   doi = {http://dx.doi.org/10.1089/jayao.2019.0064},
   keywords = {fertility impairment; fertility preservation; cryopreservation; shared decision-making; fertility-related wishes and concerns; patient education},
   language = {eng},
   issn = {2156-5333},
   journal = {JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY},
   title = {Fertility-Related Wishes and Concerns of Adolescent Cancer Patients and Their Parents},
   url = {https://www.liebertpub.com/doi/10.1089/jayao.2019.0064},
   volume = {9},
   year = {2020}
}

TY  - JOUR
ID  - 1670217
AU  - Korte, E. - Schilling, R. - Balcerek, M. - Byrne, J. - Dirksen, U. - Herrmann, G. - Kepák, Tomáš - Klco-Brosius, S. - Kruseova, J. - Kunstreich, M. - Langer, T. - Panasiuk, A. - Stefanowicz, J. - Strauss, G. - Wiegele, K. - Borgmann-Staudt, A.
PY  - 2020
TI  - Fertility-Related Wishes and Concerns of Adolescent Cancer Patients and Their Parents
JF  - JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY
VL  - 9
IS  - 1
SP  - 55-62
EP  - 55-62
PB  - MARY ANN LIEBERT, INC
SN  - 21565333
KW  - fertility impairment
KW  - fertility preservation
KW  - cryopreservation
KW  - shared decision-making
KW  - fertility-related wishes and concerns
KW  - patient education
UR  - https://www.liebertpub.com/doi/10.1089/jayao.2019.0064
L2  - https://www.liebertpub.com/doi/10.1089/jayao.2019.0064
N2  - Purpose: Within a multicenter European study, we explored fertility-related wishes, concerns, and decision-making of adolescent cancer patients and their parents. Patients and Methods: Patients and parents were each asked to complete a fertility-related questionnaire 3 months after initial diagnosis. In total, 113 of 142 (79.6%) eligible patients participated; 53.1% were male and the median age was 16 years (range 13-20 years). The questionnaire was completed by 111 parents. Univariate analyses were conducted using nonparametric methods with alpha = 5%. For multivariate analyses, binary logistic regression was conducted. Results: Both patients (86.1%) and parents (96.3%) indicated a strong desire for biological parenthood for themselves/their children. Female patients (odds ratio [OR] = 3.70; confidence interval [CI]: 1.43-9.50) and parents (OR = 2.70; CI: 1.21-6.00) were more likely to report a high fear of cancer recurrence. Patients who estimated their risk for fertility impairment being high were more likely to be concerned about their fertility (OR = 5.69; CI: 1.41-22.98). Parents who received fertility preservation information were more likely to recommend its use to their children (OR = 5.50; CI: 1.07-28.40), whereas parents of female patients were less likely to do so (OR = 0.13; CI: 0.03-0.61). Conclusions: The prospect of fertility following cancer treatment is important for adolescent cancer patients and their parents, yet it is associated with many concerns. Counseling regarding fertility preservation can be more effective when the individual needs of patients and their parents are taken into consideration.
ER  -

KORTE, E., R. SCHILLING, M. BALCEREK, J. BYRNE, U. DIRKSEN, G. HERRMANN, Tomáš KEPÁK, S. KLCO-BROSIUS, J. KRUSEOVA, M. KUNSTREICH, T. LANGER, A. PANASIUK, J. STEFANOWICZ, G. STRAUSS, K. WIEGELE and A. BORGMANN-STAUDT. Fertility-Related Wishes and Concerns of Adolescent Cancer Patients and Their Parents. \textit{JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY}. NEW ROCHELLE: MARY ANN LIEBERT, INC, 2020, vol.~9, No~1, p.~55-62. ISSN~2156-5333. Available from: https://dx.doi.org/10.1089/jayao.2019.0064.

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