Targeted Radiotherapy of the Tumor Cavity after Surgical
Resection of Aggressive Recurrent Brain Metastasis: A Case
Report

J 2020

Targeted Radiotherapy of the Tumor Cavity after Surgical Resection of Aggressive Recurrent Brain Metastasis: A Case Report

FADRUS, Pavel, Tomáš KAZDA, Petr DVORACEK, Petr POSPÍŠIL, Ludmila HYNKOVÁ et. al.

Basic information

Original name

Targeted Radiotherapy of the Tumor Cavity after Surgical Resection of Aggressive Recurrent Brain Metastasis: A Case Report

Authors

FADRUS, Pavel (203 Czech Republic, belonging to the institution), Tomáš KAZDA (203 Czech Republic, guarantor, belonging to the institution), Petr DVORACEK (203 Czech Republic), Petr POSPÍŠIL (203 Czech Republic, belonging to the institution), Ludmila HYNKOVÁ (203 Czech Republic, belonging to the institution), Jana ZITTERBARTOVÁ (203 Czech Republic, belonging to the institution), Radana DYMÁČKOVÁ (203 Czech Republic, belonging to the institution), Ivana KOLOUŠKOVÁ (203 Czech Republic, belonging to the institution), Renata BELANOVÁ (203 Czech Republic, belonging to the institution), Tomáš PROCHÁZKA (203 Czech Republic, belonging to the institution) and Pavel ŠLAMPA (203 Czech Republic, belonging to the institution)

Edition

CASE REPORTS IN ONCOLOGY, BASEL, KARGER, 2020, 1662-6575

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30204 Oncology

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

RIV identification code

RIV/00216224:14110/20:00118604

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1159/000506328

UT WoS

000533875000037

Keywords in English

Brain metastases; Radiotherapy; Local control

Abstract

V originále

Postoperative management of patients with brain metastases is controversial. Besides local control, cognitive function and quality of life are the most important outcomes of postoperative radiotherapy. In this case report, we introduce a patient with aggressive recurred solid metastasis treated with repeated surgery and an individual radiotherapy approach in order to highlight that close mutual collaboration leads to a clear benefit for our patients. The local targeted radiotherapy with 35 Gy in 10 fractions was performed with the volumetric modulated arc technique, leading to more than 2.5 years of local control and survival without any of the side effects usually attributed to whole brain radiotherapy.

Links

NV18-03-00398, research and development project

Name: Rozšíření současných prognostických skórovacích systémů u mozkových metastáz o mikroRNA profilování s cílem individualizace pooperační péče

Investor: Ministry of Health of the CR, Extension of established prognostic scores in brain metastases by microRNA profiling to tailor the post-operative personalized care

NV18-03-00469, research and development project

Name: Reakce neuronální populace hipokampu na stereotaktickou radioterapii extratemporálních mozkových metastáz: vliv na neurokognitivní funkce a zachování kvality života

Investor: Ministry of Health of the CR

Citovat

FADRUS, Pavel, Tomáš KAZDA, Petr DVORACEK, Petr POSPÍŠIL, Ludmila HYNKOVÁ, Jana ZITTERBARTOVÁ, Radana DYMÁČKOVÁ, Ivana KOLOUŠKOVÁ, Renata BELANOVÁ, Tomáš PROCHÁZKA and Pavel ŠLAMPA. Targeted Radiotherapy of the Tumor Cavity after Surgical Resection of Aggressive Recurrent Brain Metastasis: A Case Report. CASE REPORTS IN ONCOLOGY. BASEL: KARGER, 2020, vol. 13, No 1, p. 233-238. ISSN 1662-6575. Available from: https://dx.doi.org/10.1159/000506328.

@article{1670348,
   author = {Fadrus, Pavel and Kazda, Tomáš and Dvoracek, Petr and Pospíšil, Petr and Hynková, Ludmila and Zitterbartová, Jana and Dymáčková, Radana and Koloušková, Ivana and Belanová, Renata and Procházka, Tomáš and Šlampa, Pavel},
   article_location = {BASEL},
   article_number = {1},
   doi = {http://dx.doi.org/10.1159/000506328},
   keywords = {Brain metastases; Radiotherapy; Local control},
   language = {eng},
   issn = {1662-6575},
   journal = {CASE REPORTS IN ONCOLOGY},
   title = {Targeted Radiotherapy of the Tumor Cavity after Surgical Resection of Aggressive Recurrent Brain Metastasis: A Case Report},
   url = {https://www.karger.com/Article/Pdf/506328},
   volume = {13},
   year = {2020}
}

TY  - JOUR
ID  - 1670348
AU  - Fadrus, Pavel - Kazda, Tomáš - Dvoracek, Petr - Pospíšil, Petr - Hynková, Ludmila - Zitterbartová, Jana - Dymáčková, Radana - Koloušková, Ivana - Belanová, Renata - Procházka, Tomáš - Šlampa, Pavel
PY  - 2020
TI  - Targeted Radiotherapy of the Tumor Cavity after Surgical Resection of Aggressive Recurrent Brain Metastasis: A Case Report
JF  - CASE REPORTS IN ONCOLOGY
VL  - 13
IS  - 1
SP  - 233-238
EP  - 233-238
PB  - KARGER
SN  - 16626575
KW  - Brain metastases
KW  - Radiotherapy
KW  - Local control
UR  - https://www.karger.com/Article/Pdf/506328
L2  - https://www.karger.com/Article/Pdf/506328
N2  - Postoperative management of patients with brain metastases is controversial. Besides local control, cognitive function and quality of life are the most important outcomes of postoperative radiotherapy. In this case report, we introduce a patient with aggressive recurred solid metastasis treated with repeated surgery and an individual radiotherapy approach in order to highlight that close mutual collaboration leads to a clear benefit for our patients. The local targeted radiotherapy with 35 Gy in 10 fractions was performed with the volumetric modulated arc technique, leading to more than 2.5 years of local control and survival without any of the side effects usually attributed to whole brain radiotherapy.
ER  -

FADRUS, Pavel, Tomáš KAZDA, Petr DVORACEK, Petr POSPÍŠIL, Ludmila HYNKOVÁ, Jana ZITTERBARTOVÁ, Radana DYMÁČKOVÁ, Ivana KOLOUŠKOVÁ, Renata BELANOVÁ, Tomáš PROCHÁZKA and Pavel ŠLAMPA. Targeted Radiotherapy of the Tumor Cavity after Surgical Resection of Aggressive Recurrent Brain Metastasis: A Case Report. \textit{CASE REPORTS IN ONCOLOGY}. BASEL: KARGER, 2020, vol.~13, No~1, p.~233-238. ISSN~1662-6575. Available from: https://dx.doi.org/10.1159/000506328.

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