TREBICHALSKÁ, Zuzana and Zuzana HOLUBCOVÁ. Perfect date-the review of current research into molecular bases of mammalian fertilization. Journal of Assisted Reproduction and Genetics. NEW YORK: SPRINGER/PLENUM PUBLISHERS, 2020, vol. 37, No 2, p. 243-256. ISSN 1058-0468. Available from: https://dx.doi.org/10.1007/s10815-019-01679-4.
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Basic information
Original name Perfect date-the review of current research into molecular bases of mammalian fertilization
Authors TREBICHALSKÁ, Zuzana (703 Slovakia, belonging to the institution) and Zuzana HOLUBCOVÁ (203 Czech Republic, guarantor, belonging to the institution).
Edition Journal of Assisted Reproduction and Genetics, NEW YORK, SPRINGER/PLENUM PUBLISHERS, 2020, 1058-0468.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30214 Obstetrics and gynaecology
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.412
RIV identification code RIV/00216224:14110/20:00114231
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1007/s10815-019-01679-4
UT WoS 000507352700001
Keywords in English Fertilization; In vitro fertilization; Gamete biology; Human reproduction
Tags 14110517, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 15/7/2020 09:44.
Abstract
Fertilization is a multistep process during which two terminally differentiated haploid cells, an egg and a sperm, combine to produce a totipotent diploid zygote. In the early 1950s, it became possible to fertilize mammalian eggs in vitro and study the sequence of cellular and molecular events leading to embryo development. Despite all the achievements of assisted reproduction in the last four decades, remarkably little is known about the molecular aspects of human conception. Current fertility research in animal models is casting more light on the complexity of the process all our lives start with. This review article provides an update on the investigation of mammalian fertilization and highlights the practical implications of scientific discoveries in the context of human reproduction and reproductive medicine.
Links
GJ19-14990Y, research and development projectName: Ultrastrukturní znaky kvality lidských oocytů (Acronym: lidské oocyty)
Investor: Czech Science Foundation
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