J 2020

Perfect date-the review of current research into molecular bases of mammalian fertilization

TREBICHALSKÁ, Zuzana and Zuzana HOLUBCOVÁ

Basic information

Original name

Perfect date-the review of current research into molecular bases of mammalian fertilization

Authors

TREBICHALSKÁ, Zuzana (703 Slovakia, belonging to the institution) and Zuzana HOLUBCOVÁ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Journal of Assisted Reproduction and Genetics, NEW YORK, SPRINGER/PLENUM PUBLISHERS, 2020, 1058-0468

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30214 Obstetrics and gynaecology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 3.412

RIV identification code

RIV/00216224:14110/20:00114231

Organization unit

Faculty of Medicine

UT WoS

000507352700001

Keywords in English

Fertilization; In vitro fertilization; Gamete biology; Human reproduction

Tags

Tags

International impact, Reviewed
Změněno: 15/7/2020 09:44, Mgr. Tereza Miškechová

Abstract

V originále

Fertilization is a multistep process during which two terminally differentiated haploid cells, an egg and a sperm, combine to produce a totipotent diploid zygote. In the early 1950s, it became possible to fertilize mammalian eggs in vitro and study the sequence of cellular and molecular events leading to embryo development. Despite all the achievements of assisted reproduction in the last four decades, remarkably little is known about the molecular aspects of human conception. Current fertility research in animal models is casting more light on the complexity of the process all our lives start with. This review article provides an update on the investigation of mammalian fertilization and highlights the practical implications of scientific discoveries in the context of human reproduction and reproductive medicine.

Links

GJ19-14990Y, research and development project
Name: Ultrastrukturní znaky kvality lidských oocytů (Acronym: lidské oocyty)
Investor: Czech Science Foundation