LISKOVA, A., P. STEFANICKA, M. SAMEC, Karel ŠMEJKAL, P. ZUBOR, T. BIELIK, K. BISKUPSKA-BODOVA, T. K. KWON, J. DANKO, D. BUSSELBERG, M. ADAMEK, L. RODRIGO, Peter KRUŽLIAK, A. SHLEIKIN and P. KUBATKA. Dietary phytochemicals as the potential protectors against carcinogenesis and their role in cancer chemoprevention. Clinical and Experimental Medicine. Milan: SPRINGER-VERLAG ITALIA SRL, 2020, vol. 20, No 2, p. 173-190. ISSN 1591-8890. Available from: https://dx.doi.org/10.1007/s10238-020-00611-w.
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Basic information
Original name Dietary phytochemicals as the potential protectors against carcinogenesis and their role in cancer chemoprevention
Authors LISKOVA, A. (703 Slovakia), P. STEFANICKA (703 Slovakia), M. SAMEC (703 Slovakia), Karel ŠMEJKAL (203 Czech Republic, belonging to the institution), P. ZUBOR (703 Slovakia), T. BIELIK (703 Slovakia), K. BISKUPSKA-BODOVA (703 Slovakia), T. K. KWON (410 Republic of Korea), J. DANKO (703 Slovakia), D. BUSSELBERG (634 Qatar), M. ADAMEK (616 Poland), L. RODRIGO (724 Spain), Peter KRUŽLIAK (703 Slovakia, guarantor, belonging to the institution), A. SHLEIKIN (643 Russian Federation) and P. KUBATKA (703 Slovakia).
Edition Clinical and Experimental Medicine, Milan, SPRINGER-VERLAG ITALIA SRL, 2020, 1591-8890.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30308 Nutrition, Dietetics
Country of publisher Italy
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.984
RIV identification code RIV/00216224:14110/20:00115989
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1007/s10238-020-00611-w
UT WoS 000518152000001
Keywords in English Carcinogens; Dietary phytochemicals; Antioxidant; Scavenging effect; Detoxification; Metabolic activation; Chemoprevention
Tags 14110121, podil, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 4/5/2021 13:03.
Abstract
Health-threatening consequences of carcinogen exposure are mediated via occurrence of electrophiles or reactive oxygen species. As a result, the accumulation of biomolecular damage leads to the cancer initiation, promotion or progression. Accordingly, there is an association between lifestyle factors including inappropriate diet or carcinogen formation during food processing, mainstream, second or third-hand tobacco smoke and other environmental or occupational carcinogens and malignant transformation. Nevertheless, increasing evidence supports the protective effects of naturally occurring phytochemicals against carcinogen exposure as well as carcinogenesis in general. Isolated phytochemicals or their mixtures present in the whole plant food demonstrate efficacy against malignancy induced by carcinogens widely spread in our environment. Phytochemicals also minimize the generation of carcinogenic substances during the processing of meat and meat products. Based on numerous data, selected phytochemicals or plant foods should be highly recommended to become a stable and regular part of the diet as the protectors against carcinogenesis.
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