J 2020

Dietary phytochemicals as the potential protectors against carcinogenesis and their role in cancer chemoprevention

LISKOVA, A., P. STEFANICKA, M. SAMEC, Karel ŠMEJKAL, P. ZUBOR et. al.

Basic information

Original name

Dietary phytochemicals as the potential protectors against carcinogenesis and their role in cancer chemoprevention

Authors

LISKOVA, A. (703 Slovakia), P. STEFANICKA (703 Slovakia), M. SAMEC (703 Slovakia), Karel ŠMEJKAL (203 Czech Republic, belonging to the institution), P. ZUBOR (703 Slovakia), T. BIELIK (703 Slovakia), K. BISKUPSKA-BODOVA (703 Slovakia), T. K. KWON (410 Republic of Korea), J. DANKO (703 Slovakia), D. BUSSELBERG (634 Qatar), M. ADAMEK (616 Poland), L. RODRIGO (724 Spain), Peter KRUŽLIAK (703 Slovakia, guarantor, belonging to the institution), A. SHLEIKIN (643 Russian Federation) and P. KUBATKA (703 Slovakia)

Edition

Clinical and Experimental Medicine, Milan, SPRINGER-VERLAG ITALIA SRL, 2020, 1591-8890

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30308 Nutrition, Dietetics

Country of publisher

Italy

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 3.984

RIV identification code

RIV/00216224:14110/20:00115989

Organization unit

Faculty of Medicine

UT WoS

000518152000001

Keywords in English

Carcinogens; Dietary phytochemicals; Antioxidant; Scavenging effect; Detoxification; Metabolic activation; Chemoprevention

Tags

International impact, Reviewed
Změněno: 4/5/2021 13:03, Mgr. Tereza Miškechová

Abstract

V originále

Health-threatening consequences of carcinogen exposure are mediated via occurrence of electrophiles or reactive oxygen species. As a result, the accumulation of biomolecular damage leads to the cancer initiation, promotion or progression. Accordingly, there is an association between lifestyle factors including inappropriate diet or carcinogen formation during food processing, mainstream, second or third-hand tobacco smoke and other environmental or occupational carcinogens and malignant transformation. Nevertheless, increasing evidence supports the protective effects of naturally occurring phytochemicals against carcinogen exposure as well as carcinogenesis in general. Isolated phytochemicals or their mixtures present in the whole plant food demonstrate efficacy against malignancy induced by carcinogens widely spread in our environment. Phytochemicals also minimize the generation of carcinogenic substances during the processing of meat and meat products. Based on numerous data, selected phytochemicals or plant foods should be highly recommended to become a stable and regular part of the diet as the protectors against carcinogenesis.