Detailed Information on Publication Record
2020
Dietary phytochemicals as the potential protectors against carcinogenesis and their role in cancer chemoprevention
LISKOVA, A., P. STEFANICKA, M. SAMEC, Karel ŠMEJKAL, P. ZUBOR et. al.Basic information
Original name
Dietary phytochemicals as the potential protectors against carcinogenesis and their role in cancer chemoprevention
Authors
LISKOVA, A. (703 Slovakia), P. STEFANICKA (703 Slovakia), M. SAMEC (703 Slovakia), Karel ŠMEJKAL (203 Czech Republic, belonging to the institution), P. ZUBOR (703 Slovakia), T. BIELIK (703 Slovakia), K. BISKUPSKA-BODOVA (703 Slovakia), T. K. KWON (410 Republic of Korea), J. DANKO (703 Slovakia), D. BUSSELBERG (634 Qatar), M. ADAMEK (616 Poland), L. RODRIGO (724 Spain), Peter KRUŽLIAK (703 Slovakia, guarantor, belonging to the institution), A. SHLEIKIN (643 Russian Federation) and P. KUBATKA (703 Slovakia)
Edition
Clinical and Experimental Medicine, Milan, SPRINGER-VERLAG ITALIA SRL, 2020, 1591-8890
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30308 Nutrition, Dietetics
Country of publisher
Italy
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 3.984
RIV identification code
RIV/00216224:14110/20:00115989
Organization unit
Faculty of Medicine
UT WoS
000518152000001
Keywords in English
Carcinogens; Dietary phytochemicals; Antioxidant; Scavenging effect; Detoxification; Metabolic activation; Chemoprevention
Tags
International impact, Reviewed
Změněno: 4/5/2021 13:03, Mgr. Tereza Miškechová
Abstract
V originále
Health-threatening consequences of carcinogen exposure are mediated via occurrence of electrophiles or reactive oxygen species. As a result, the accumulation of biomolecular damage leads to the cancer initiation, promotion or progression. Accordingly, there is an association between lifestyle factors including inappropriate diet or carcinogen formation during food processing, mainstream, second or third-hand tobacco smoke and other environmental or occupational carcinogens and malignant transformation. Nevertheless, increasing evidence supports the protective effects of naturally occurring phytochemicals against carcinogen exposure as well as carcinogenesis in general. Isolated phytochemicals or their mixtures present in the whole plant food demonstrate efficacy against malignancy induced by carcinogens widely spread in our environment. Phytochemicals also minimize the generation of carcinogenic substances during the processing of meat and meat products. Based on numerous data, selected phytochemicals or plant foods should be highly recommended to become a stable and regular part of the diet as the protectors against carcinogenesis.