VALIS, Martin, Jana SARLAKOVA, Simona HALUSKOVA, Blanka KLIMOVA, Pavel POTUZNIK, Marek PETERKA, Kamil KUCA, Pavel ŠTOURAČ, Jan MARES and Zbysek PAVELEK. An observational study demonstrating the adherence and ease of use of the injector device, RebiSmart (R). EXPERT OPINION ON DRUG DELIVERY. ABINGDON: TAYLOR & FRANCIS LTD, 2020, vol. 17, No 5, p. 719-724. ISSN 1742-5247. Available from: https://dx.doi.org/10.1080/17425247.2020.1742694.
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Basic information
Original name An observational study demonstrating the adherence and ease of use of the injector device, RebiSmart (R)
Authors VALIS, Martin (203 Czech Republic), Jana SARLAKOVA (203 Czech Republic), Simona HALUSKOVA (203 Czech Republic), Blanka KLIMOVA (203 Czech Republic), Pavel POTUZNIK (203 Czech Republic), Marek PETERKA (203 Czech Republic), Kamil KUCA (203 Czech Republic), Pavel ŠTOURAČ (203 Czech Republic, belonging to the institution), Jan MARES (203 Czech Republic) and Zbysek PAVELEK (203 Czech Republic).
Edition EXPERT OPINION ON DRUG DELIVERY, ABINGDON, TAYLOR & FRANCIS LTD, 2020, 1742-5247.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30104 Pharmacology and pharmacy
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 6.648
RIV identification code RIV/00216224:14110/20:00116023
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1080/17425247.2020.1742694
UT WoS 000528167500001
Keywords in English Multiple Sclerosis; patients; adherence; treatment; use; RebiSmart
Tags 14110221, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 17/7/2020 09:05.
Abstract
Background: Adherence to Multiple Sclerosis (MS) treatment is considered one of the crucial factors for ensuring optimal clinical outcomes. Research has shown that the use of self-injector devices improves patient compliance with treatment. Therefore, the main purpose of this study is to evaluate the ease of use of RebiSmart (R) 2.0 in clinically isolated syndrome/relapsing-remitting MS patients during 12 months treatment period. Methods: A total number of 290 subjects entered into data collection; 249 (86%) of them completed the whole 12 months study period. The primary endpoints and the secondary endpoints were assessed by the User Study Questionnaire. Adherence data were retrieved from RebiSmart (R) 2.0 (Menu - Dose History) on the respective patient's visit. Outcome measures also included Expanded Disability Status Score, Kurtzke Functional Systems, and Modified Social Support Survey, Modified Social Support Survey-5. Results: This study demonstrated a very high proportion (>95%) of patients with a positive rating of the overall ease of use and the overall convenience of RebiSmart (R). The proportion of patients with a positive rating of the ease of use by individual domains and the functions of RebiSmart (R) were also high (>80%). Conclusion: The findings demonstrate a very good perception of the usability of the device by patients overall and in its individual functions.
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